大承气汤联合复苏合剂加减救治急性肠梗阻合并脓毒性休克的治疗体会  

Treatment of acute intestinal obstruction complicated with septic shock with Dachengqi decoction and Fusu agent

作　　者：丁鹏 周媛 周秀娟 张松[1] 高培阳[1] Ding Peng;Zhou Yuan;Zhou Xiujuan;Zhang Song;Gao Peiyang(Department of Critical Care Medicine,Hospital of Chengdu University of Traditional Chinese Medicine,Chengdu 610072,Sichuan,China;Department of Cadres'Ward,General Hospital of Western Theater Command of the Chinese People's Liberation Army,Chengdu 610083,Sichuan,China)

机构地区：[1]成都中医药大学附属医院重症医学科,四川成都610072 [2]解放军西部战区总医院干部病房,四川成都610083

出　　处：《中国中西医结合急救杂志》2024年第3期342-345,共4页Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care

基　　金：国家自然科学基金(81873298);四川省科技计划项目(22ZDYF0685);成都中医药大学附属医院科技发展基金(20ZL10)。

摘　　要：目的分析脑出血术后急性肠梗阻的原因,以及大承气汤联合复苏合剂加减直肠滴入对急性肠梗阻合并脓毒性休克的治疗作用。方法回顾性分析2022年3月5日成都中医药大学附属医院收治的1例脑出血术后急性肠梗阻合并脓毒性休克患者的临床资料,观察中药直肠滴入治疗对肠道功能恢复和休克改善的影响。结果患者男性,52岁,因脑出血于2022年2月19日行“左侧颞部开颅颅内减压术+颅脑血肿清除术+脑脊液漏修补术”。术后7 d,患者出现呃逆、腹胀,经治疗后出现发热、意识障碍、低血压等表现;腹部CT可见广泛肠管积液、积气、扩张,血流动力学监测呈高排低阻型,腹内压为21 cmH_(2)O(1 cmH_(2)O≈0.098 kPa),实验室检查示炎症指标升高、多项生化指标异常。西医诊断为急性肠梗阻合并脓毒性休克,给予器官支持(肺、循环、肾)、抗感染、液体复苏、镇痛镇静等对症治疗;中医诊断为肠结(阳明腑实、阳气暴脱),治则:通腑泄热、温肾潜阳,辨证大承气汤联合复苏合剂加减经直肠给药。使用中医汤剂后,患者排便量明显增多,腹内压降至正常参考值范围,腹胀明显减轻,休克得到缓解。术后17 d,患者诸症好转,呼吸循环稳定,成功转出重症监护病房(ICU)。结论大承气汤联合复苏合剂加减直肠滴入治疗急性肠梗阻合并脓毒性休克患者,可快速缓解病情,促进肠道功能恢复。Objective To analyze the causes of acute intestinal obstruction after intracerebral hemorrhage,and the therapeutic effect of rectal dripping with Dachengqi decoction and Fusu agent on acute intestinal obstruction complicated with septic shock.Methods The clinical data of a patient with acute intestinal obstruction complicated with septic shock after intracerebral hemorrhage,who was admitted to the Hospital of Chengdu University of Traditional Chinese Medicine(TCM)on March 5,2022,were retrospectively analyzed.The study aimed to observe the effects of rectal dripping with TCM on the recovery of intestinal function and improvement of shock.Results The patient was a 52-year-old male who underwent"left temporal craniotomy intracranial decompression,craniocerebral hematoma removal,cerebrospinal fluid leak repair"on February 19,2022 due to cerebral hemorrhage.On the 7th day after operation,the patient had hiccups and abdominal distension,and after treatment,the patient developed fever,consciousness disorders,hypotension and other symptoms.Abdominal CT showed extensive intestinal fluid,gas and expansion.Hemodynamic monitoring indicated high discharge and low resistance,intra-abdominal pressure was 21 cmH2O(1 cmH2O≈0.098 kPa),and laboratory examination showed increased inflammatory indexes and abnormal biochemical indexes.The western medicine diagnosis was acute intestinal obstruction complicated with septic shock,and the symptomatic treatments such as organ support(lung,circulation,kidney),anti-infection,fluid resuscitation,analgesia and sedation were given.The TCM diagnosis was intestinal knot(yangming visceral substantive,sudden collapse of yang-qi),with treatment principles focusing on tongfu heat relief,wenshen qianyang,Dachengqi decoction and Fusu agent was added and reduced according to the syndrome differentiation,with medications administered rectally.After the use of TCM decoction,the patient's defecation volume increased significantly,the intra-abdominal pressure decreased to the normal range,abdominal disten

关 键 词：急性肠梗阻 脓毒性休克 大承气汤 复苏合剂 腹胀 腹内高压 

分 类 号：R574[医药卫生—消化系统]