阿尔茨海默病发病机制的研究进展  

Advancements in the Pathogenesis Research of Alzheimer's Disease

作　　者：鲁西 骆晓峰 宋毓 刘永超 孙新 李春颖 Lu Xi;Luo Xiaofeng;Song Yu;Liu Yongchao;Sun Xin;Li Chunying(Medical Technology College of Beihua University,Jilin 132000;Basic Medical College,Jilin Medical University,Jilin 132000;College of Pharmacy,Jilin Medical University,Jilin 132000)

机构地区：[1]北华大学医学技术学院,吉林132000 [2]吉林医药学院基础医学院,吉林132000 [3]吉林医药学院药学院,吉林132000

出　　处：《国际老年医学杂志》2024年第5期619-623,共5页International Journal of Geriatrics

基　　金：吉林省科技发展计划项目(202002001JC,20220402072GH);吉林省卫生与健康技术创新项目(2020J016);吉林省“十三五”科学技术研究规划项目(JJKH20190638KJ);吉林省发展和改革委员会项目(2021C007);吉林市科技创新发展计划(2021001395);吉林医药学院博士基金(JYBS2023004LK,JYBS2021026LK)。

摘　　要：随着我国人口老龄化问题的日趋严重,与衰老密切相关的老年痴呆人数也不断增长,阿尔茨海默病(AD)是引起老年痴呆最常见的病因,对患者及家庭造成了严重的经济和精神负担,因此对于脑衰老及AD的研究已经成为迫切需求。本文就近年来AD的发病机制进行综述,为脑衰老造成的神经退行性AD等疾病提供参考。With China's aging population on the rise,the incidence of senile dementia,particularly neurodegenerative diseases Alzheimer's disease(AD),is also increasing,leading to significant economic and emotional burdens for patients and their families.Consequently,research on brain senescence and AD has become imperative.This review delves into recent advancements in understanding the pathogenesis of AD,offering crucial insights into the neurodegenerative processes associated with brain senescence and informing strategies for managing and treating AD and related conditions.

关 键 词：脑衰老 发病机制 神经退行性疾病 阿尔茨海默病 

分 类 号：R749.16[医药卫生—神经病学与精神病学]