超微细血管成像技术与彩色多普勒血流成像的Adler分级对乳腺癌辅助化疗疗效的评估价值  

Evaluation value of Adler grading of superb microvascular imaging and color Doppler flow imaging in efficacy of adjuvant chemotherapy for breast cancer

作　　者：赵哲 骈林萍[1] 赵迎[1] 习广晓 王林莹 安超[1] 陈杰[1] ZHAO Zhe;PIAN Linping;ZHAO Ying;XI Guangxiao;WANG Linying;AN Chao;CHEN Jie(Department of Ultrasound,the First Affiliated Hospital of He’nan University of Traditional Chinese Medicine,Zhengzhou 450000,He’nan,China)

机构地区：[1]河南中医药大学第一附属医院超声科,郑州4500000

出　　处：《癌症进展》2024年第15期1637-1640,共4页Oncology Progress

基　　金：河南省中医药科学研究专项课题(2023ZY2051)。

摘　　要：目的 探讨超声超微细血管成像技术(SMI)与彩色多普勒血流成像(CDFI)的Adler分级对乳腺癌辅助化疗疗效的评估价值。方法 选取108例进行辅助化疗的乳腺癌患者,均进行SMI、CDFI检查。比较化疗前后SMI和CDFI的Adler分级,并分析其对化疗疗效的评估价值。比较化疗前不同肿瘤最大径和分期乳腺癌患者CDFI的Adler分级。结果 化疗前后,乳腺癌患者SMI、CDFI的Adler分级比较,差异均有统计学意义(P﹤0.01)。CDFI的Adler分级评估化疗疗效的灵敏度为91.9%(68/74),特异度为79.4%(27/34),准确度为88.0%(95/108),与疗效评价结果的一致性Kappa值为0.719。SMI的Adler分级评估化疗疗效的灵敏度为94.6%(70/74),特异度为76.5%(26/34),准确度为88.9%(96/108),与疗效评价结果的一致性Kappa值为0.733。化疗前不同肿瘤最大径和分期乳腺癌患者CDFI的Adler分级比较,差异均有统计学意义(P﹤0.01)。结论 SMI和CDFI的Adler分级对乳腺癌辅助化疗疗效均具有一定的评估价值,并且SMI诊断效能更高。Objective To investigate evaluation value of Adler grading of superb microvascular imaging(SMI)and color Doppler flow imaging(CDFI)in efficacy of adjuvant chemotherapy for breast cancer.Method A total of 108 pa-tients with breast cancer receiving adjuvant chemotherapy were examined by SMI and CDFI.The Adler grades of SMI and CDFI before and after chemotherapy were compared,and their values in evaluating the efficacy of chemotherapy were analyzed.The Adler grade of CDFI in breast cancer patients with different tumor maximum diameter and stage be-fore chemotherapy were compared.Result Before and after chemotherapy,there were significant differences in Adler grades of SMI and CDFI in breast cancer patients(P<0.01).The sensitivity,specificity and accuracy of CDFI Adler grad-ing for evaluating chemotherapy efficacy were 91.9%(68/74),79.4%(27/34)and 88.0%(95/108),and the Kappa value of agreement with the efficacy evaluation results was 0.719.The sensitivity,specificity and accuracy of SMI Adler grad-ing for evaluating chemotherapy efficacy were 94.6%(70/74),76.5%(26/34)and 88.9%(96/108),and the Kappa value of agreement with the efficacy evaluation results was 0.733.The Adler grades of CDFI in breast cancer patients with dif-ferent tumor maximum diameter and stages before chemotherapy were statistically significant(P<0.01).Conclusion The Adler grading of SMI and CDFI has certain value in evaluating the efficacy of adjuvant chemotherapy for breast can-cer,and SMI has higher diagnostic efficacy.

关 键 词：超微细血管成像技术 彩色多普勒血流成像 Adler分级 乳腺癌 化疗疗效 

分 类 号：R737.9[医药卫生—肿瘤]