心理弹性干预联合对症支持对乳腺癌易感基因突变晚期卵巢癌患者心理弹性及生活质量的影响  

Effects of psychological resilience intervention combined with symptomatic support on mental resilience and quality of life in patients with advanced ovarian cancer with breast cancer susceptibility gene mutation

作　　者：孙玉树 赵威[1] 李孟玮 SUN Yushu;ZHAO Wei;LI Mengwei(Department of Obstetrics and Gynecology,the Third Affiliated Hospital of He’nan University of Traditional Chinese Medicine,Zhengzhou 450000,He’nan,China)

机构地区：[1]河南中医药大学第三附属医院妇产科,郑州4500000

出　　处：《癌症进展》2024年第15期1671-1675,共5页Oncology Progress

基　　金：河南省中医药科学研究专项课题(20-21ZY2220)。

摘　　要：目的 探讨心理弹性干预联合对症支持对乳腺癌易感基因(BRCA)突变晚期卵巢癌患者心理弹性和生活质量的影响。方法 将80例BRCA突变晚期卵巢癌患者按干预方法的不同分为联合心理干预组(n=43)和常规干预组(n=37),常规干预组患者采用常规疗护方法,联合心理干预组患者在常规干预组的基础上采用心理弹性干预联合对症支持。比较两组患者心理弹性[心理弹性量表(CD-RISC)]、疼痛[数字分级评分法(NRS)]、自我效能[一般自我效能感量表(GSES)]、心理状况[症状自评量表(SCL-90)]、生活质量[欧洲癌症研究与治疗组织生命质量测定量表(EORTC QLQ-C30)]和满意度。结果 干预后,两组患者CD-RISC、EORTC QLQ-C30各维度评分均较干预前升高,SCL-90各维度评分均较干预前降低,且联合心理干预组患者CD-RISC、EORTC QLQ-C30各维度评分均高于常规干预组,SCL-90各维度评分均低于常规干预组,差异均有统计学意义(P﹤0.05)。干预后,两组患者NRS评分均较干预前降低,GSES评分均较干预前升高,且联合心理干预组患者NRS评分低于常规干预组,GSES评分高于常规干预组,差异均有统计学意义(P﹤0.05)。联合心理干预组患者满意度和满意度评分均高于常规干预组,差异均有统计学意义(P﹤0.05)。结论 心理弹性干预联合对症支持可有效提升BRCA突变晚期卵巢癌患者心理弹性、自我效能、生活质量,减轻疼痛,缓解负性情绪,提高患者满意度。Objective To investigate the effects of psychological resilience intervention combined with symptomatic support on mental resilience and quality of life in patients with advanced ovarian cancer with breast cancer susceptibility gene(BRCA)mutation.Method A total of 80 patients with advanced ovarian cancer with BRCA mutation were divided into combined psychological intervention group(n=43)and conventional intervention group(n=37)according to different intervention methods.The conventional intervention group was treated with routine care,and the combined psychological intervention group was treated with psychological resilience intervention combined with symptomatic support on the ba-sis of the conventional intervention group.Mental resilience[Connor-Davidson resilience scale(CD-RISC)],pain[numer-ical rating scale(NRS)],self-efficacy[general self-efficacy scale(GSES)],mental status[symptom check list 90(SCL-90)],quality of life[European Organization for Research and Treatment of Cancer quality of life questionnaire core 30(EORTC QLQ-C30)]and satisfaction were compared between the two groups.Result After intervention,all dimensions scores of CD-RISC and EORTC QLQ-C30 in both groups were higher than those before intervention,and all dimensions scores of SCL-90 were lower than those before intervention,and all dimensions scores of CD-RISC and EORTC QLQ-C30 in the combined psychological intervention group were higher than those in the conventional intervention group,all dimensions scores of SCL-90 were lower than those in the conventional intervention group,and the differences were sta-tistically significant(P<0.05).After intervention,the NRS scores of both groups were lower than those before interven-tion,and the GSES scores were higher than those before intervention,the NRS score of the combined psychological inter-vention group was lower than that of the conventional intervention group,and the GSES score was higher than that of the conventional intervention group,the differences were statistically significant(P<0.05)

关 键 词：心理弹性干预 对症支持 晚期卵巢癌 乳腺癌易感基因 生活质量 

分 类 号：R737.31[医药卫生—肿瘤]