钛种植体抗菌化修饰的研究进展  

Research progress on antimicrobial modification of titanium implants

作　　者：张政 杨锋 李家锋 曹焜 Zhang Zheng;Yang Feng;Li Jiafeng;Cao Kun(School of Stomatology,Xuzhou Medical University,Xuzhou 221009,China;Dept.of Stomatology,the Affiliated Hospital of Xuzhou Medical University,Xuzhou 221002,China)

机构地区：[1]徐州医科大学口腔医学院,徐州221009 [2]徐州医科大学附属医院口腔科,徐州221002

出　　处：《国际口腔医学杂志》2024年第5期585-595,共11页International Journal of Stomatology

摘　　要：种植体周围炎是导致种植失败的主要原因之一,钛基材料种植体缺乏抗菌能力,所以通过对种植体表面进行元素掺杂和形貌改性来提高种植体的抗菌能力,预防种植体周围炎,是提高种植成功率的有效可行的研究方法。然而,受限于其制作高成本、流程复杂、抗菌效果不尽稳定,目前临床中鲜有应用含抗菌修饰结构的种植体。本文从种植体抗菌材料的分类切入,叙述其抗菌机制及抗菌效果,重点介绍了口腔种植体抗菌材料的研究现状及新进展,并且归纳总结抗菌材料研究存在的难点。Peri-implantitis is a primary cause of implant failure,and titanium-based implant materials lack antimicrobial properties.Therefore,enhancing the antimicrobial capability of implants by surface modification and element doping has been identified as an effective and feasible research method to improve the antimicrobial ability of implants and prevent peri-implantitis,thereby enhancing the success rate of dental implants.However,the clinical application of implants with antimicrobial structures is currently limited because of the high production costs,complex processes,and inconsistent antimicrobial effects associated with their fabrication.Moreover,implants with antimicrobial structures,which are used in clinical practice,are limited.Thus,this review classifies implant antibacterial materials and describes their antibacterial mechanisms and antibacterial effects.Furthermore,it summarizes the challenges encountered in antimicrobial material research.

关 键 词：钛种植体 表面改性 抗菌涂层 

分 类 号：R783.1[医药卫生—口腔医学]