急性缺血性卒中合并胃肠道损伤的临床特点及高危因素分析  

Clinical characteristics and high-risk factors analysis of acute ischemic stroke combined with gastrointestinal injury

作　　者：陈琳 张永成 欧阳至吉 罗新新 Chen Lin;Zhang Yong-cheng;Ouyang Zhi-ji;Luo Xin-xin(Department of Neurology,The Affiliated Hospital of Jinggangshan University,Ji'an 343000,Jiangxi,China)

机构地区：[1]井冈山大学附属医院神经内科,江西吉安343000

出　　处：《四川生理科学杂志》2024年第9期1895-1898,共4页

基　　金：吉安市指导性科技计划项目(编号:20222-026765)。

摘　　要：目的:分析急性缺血性卒中合并胃肠道损伤(GI)的临床特点及高危因素。方法:选取本院2021年1月至2023年12月收治的500例急性缺血性卒中患者进入研究。记录合并GI发生率。比较合并GI组和无GI组间临床资料、实验室检测指标等差异,采用Logistic回归分析急性缺血性卒中合并GI高危因素。结果:500例急性缺血性卒中出现GI患者36例,合并GI发生率为7.20%。合并GI组在年龄、饮酒史、吸烟史、高血压、冠心病、糖尿病、抗生素药物使用、镇静药使用和入院NIHSS评分间与无GI组具有显著性差异(P<0.05),其余临床资料无显著性差异(P>0.05);合并GI组在白细胞计数和C-反应蛋白间与无GI组具有显著性差异(P<0.05),其余实验室检测指标无显著性差异(P>0.05);糖尿病、抗生素药物使用、镇静药使用、入院NIHSS评分和C-反应蛋白是影响急性缺血性卒中合并GI高危因素(均P<0.05)。结论:急性缺血性卒中合并GI发生率较高,糖尿病、抗生素药物使用、镇静药使用、入院NIHSS评分和C-反应蛋白是影响急性缺血性卒中合并GI高危因素。Objective:To analyze the clinical characteristics and high-risk factors of acute ischemic stroke combined with gastrointestinal injury(GI).Methods:500 patients with acute ischemic stroke admitted to our hospital from January 2021 to December 2023 were selected for the study.Record the incidence of merging GI.Compare the clinical data,laboratory testing indicators,and other differences between the combined GI group and the non GI group,and use logistic regression to analyze the high-risk factors for acute ischemic stroke combined with GI.Results:Among 500 cases of acute ischemic stroke,36 patients had GI,and the incidence of concurrent GI was 7.20%.There were significant differences between the group with GI and the group without GI in age,drinking history,smoking history,hypertension,coronary heart disease,diabetes,use of antibiotics,use of sedatives and NIHSS scores on admission(P<0.05),and there were no significant differences in other clinical data(P>0.05);There was a significant difference in white blood cell count and C-reactive protein between the combined GI group and the non GI group(P<0.05),while there was no significant difference in other laboratory test indicators(P>0.05);Diabetes,use of antibiotics,use of sedatives,NIHSS score on admission and C-reactive protein were the high risk factors for acute ischemic stroke with GI(all P<0.05).Conclusion:The incidence of acute ischemic stroke with GI is high,and diabetes,use of antibiotics,use of sedatives,NIHSS score on admission and C-reactive protein are high risk factors for acute ischemic stroke with GI.

关 键 词：急性缺血性卒中 胃肠道损伤 临床特点 高危因素 

分 类 号：R743.3[医药卫生—神经病学与精神病学]