艾司奥美拉唑辅助内镜下钛夹止血在急性上消化道出血治疗中的应用  

Application of endoscopic titanium clip hemostasis combined with esomeprazole in the treatment of acute upper gastrointestinal bleeding

作　　者：吕荣燚 冯淞 方中平 Lv Rong-yi;Feng Song;Fang Zhong-ping(Department of Emergency Medicine,Xinyang Central Hospital,Xinyang 464000,Henan,China)

机构地区：[1]信阳市中心医院急诊医学科,河南信阳464000

出　　处：《四川生理科学杂志》2024年第9期2006-2008,共3页

摘　　要：目的:探讨艾司奥美拉唑辅助内镜下钛夹止血治疗急性上消化道出血的效果,并分析其安全性。方法:回顾性分析2022年7月至2023年10月信阳市中心医院收治的86例急性上消化道出血患者临床资料,以治疗方法不同分为对照组(内镜下钛夹止血,42例)、观察组(艾司奥美拉唑辅助内镜下钛夹止血治疗,44例)。于首次内镜下钛夹止血治疗后3 d、5d比较两组再出血情况、临床指标(治疗期间输血量、住院时间)及术后不良反应发生情况。结果:观察组治疗后3d再出血率显著低于对照组(P<0.05);两组治疗后5d再出血率均降低,且观察组低于对照组,但差异无统计学意义(P>0.05)。观察组的输血量显著少于对照组,且住院时间显著短于对照组(P<0.05)。两组的不良反应发生率比较,差异不显著(P>0.05)。结论:艾司奥美拉唑辅助内镜下钛夹止血治疗急性上消化道出血,可降低再出血率,减少输血量,促进患者恢复,且安全性高。Objective:To explore the efficacy of esomeprazole assisted endoscopic titanium clip hemostasis in the treatment of acute upper gastrointestinal bleeding,and analyze its safety.Method:Aretrospective analysis was conducted on the clinical data of 86 patients with acute upper gastrointestinal bleeding admitted to Xinyang Central Hospital from July 2022 to October 2023.They were divided into a control group(42 cases)and an observation group(44 cases)based on different treatment methods,using titanium clips under endoscopy for hemostasis.The re bleeding situation,clinical indicators(blood transfusion volume during treatment,hospital stay),and incidence of postoperative adverse reactions were compared between the two groups 3 and 5 days after the first endoscopic titanium clip hemostasis treatment.Result:The rate of rebleeding in the observation group after 3 days of treatment was significantly lower than that in the control group(P<0.05).The rate of rebleeding after 5 days of treatment in both groups decreased,and the observation group was lower than the control group,but the difference was not statistically significant(P>0.05).The blood transfusion volume of the observation group was significantly lower than that of the control group,and the hospitalization time was significantly shorter than that of the control group(P<0.05).The incidence of adverse reactions between the two groups was not significantly different(P>0.05).Conclusion:Endoscopic titanium clip hemostasis combined with esomeprazole in the treatment of acute upper gastrointestinal bleeding can reduce the rate of rebleeding,reduce blood transfusion volume,promote patient recovery,and have high safety.

关 键 词：急性上消化道出血 艾司奥美拉唑 内镜下钛夹止血 再出血 安全性 

分 类 号：R573.2[医药卫生—消化系统]