内镜下氩气凝固术联合高频电刀治疗胃肠息肉效果对比分析  

Comparative Analysis of the Effectiveness of Endoscopic Argon Coagulation Combined with High-frequency Electric Knife in the Treatment of Gastrointestinal Polyps

作　　者：吕艳平 齐伟平 李克锋 LYU Yanping;QI Weiping;LI Kefeng(Department of Gastroenterology,Juye County North City Hospital,Heze 274900,Shandong,China;Department of Rehabilitation,Juye County Maternal and Child Health Hospital,Heze 274900,Shandong,China)

机构地区：[1]山东省菏泽市巨野县北城医院消化内科,山东菏泽274900 [2]山东省菏泽市巨野县妇幼保健院康复科,山东菏泽274900

出　　处：《世界复合医学》2024年第5期120-123,128,共5页World Journal of Complex Medicine

摘　　要：目的 探究内镜下氩气凝固术联合高频电刀治疗胃肠息肉的效果。方法 选取2022年6月—2023年10月山东省菏泽市巨野县北城医院消化内科收治的100例胃肠息肉患者为研究对象,根据不同治疗方法分为两组,各50例。对照组给予单纯高频电刀治疗,观察组采用内镜下氩气凝固术联合高频电刀治疗。比较两组围术期指标(术中出血量、息肉切除时间、胃肠功能恢复时间、视觉模拟评分)、胃肠道激素(胃动素、胃泌素、血管活性肠肽)、炎症因子(C-反应蛋白、降钙素原、白细胞计数)水平及并发症发生率。结果 观察组胃肠道激素胃动素[(241.05±18.24)pg/mL]、胃泌素[(129.54±16.95)pg/mL]、血管活性肠肽[(40.01±6.18)pg/mL]水平均优于对照组[(227.69±17.46)pg/mL、(112.72±17.36)pg/mL、(46.49±5.69)pg/mL],差异有统计学意义(t=3.741、4.902、5.454,P均<0.05)。观察组术中出血量、息肉切除时间、术后胃肠功能恢复时间、视觉模拟评分、C-反应蛋白、白细胞计数、降钙素原水平以及并发症总发生率均优于对照组,差异有统计学意义(P均<0.05)。结论 在围术期指标、胃肠道激素和炎症因子水平及并发症发生率方面,内镜下氩气凝固术联合高频电刀治疗均优于单纯高频电刀治疗,具有更好的疗效和安全性。Objective To investigate the effect of endoscopic argon coagulation combined with highfrequency electric knife in the treatment of gastrointestinal polyps.Methods A total of 100 patients with gastrointestinal polyps admitted to the Department of Gastroenterology in Juye County North City Hospital from June 2022 to October 2023 were selected as the study subjects,and they were divided into two groups of 50 cases each according to the different treatment method.The control group was given simple high-frequency electric knife treatment,and the observation group was treated with endoscopic argon coagulation combined with highfrequency electric knife.The perioperative indexes(intraoperative bleeding,poly removal time,postoperative gastrointestinal function recovery time,Visual Analogue Score),gastrointestinal hormones(gastric actin,gastrin,vasoactive intestinal peptide),inflammatory factors(C-reactive protein,procalcitonin,white blood cell count)levels and complication rates of the two groups were compared.Results The levels of gastrointestinal hormones gastric actin [(241.05±18.24) pg/mL],gastrin [(129.54±16.95) pg/mL],and vasoactive intestinal peptide [(40.01±6.18) pg/mL] in the observation group were better than [(227.69±17.46) pg/mL,(112.72±17.36) pg/mL,(46.49±5.69) pg/mL] in the control group,and the differences were statistically significant(t=3.741,4.902,5.454,all P<0.05).Intraoperative bleeding,polyp removal time,postoperative gastrointestinal function recovery time,Visual Analog Score,C-reactive protein,white blood cell count,procalcitonin level,and the total incidence of adverse reactions in the observation group were better than those in the control group,and the differences were statistically significant(all P<0.05).Conclusion Endoscopic argon coagulation combined with highfrequency electric knife is superior to high-frequency electric knife alone in terms of perioperative indexes,gastrointestinal hormone and inflammatory factor levels,and complication rates,and has better efficacy and safety.

关 键 词：高频电刀治疗 胃肠息肉 胃肠道激素 炎症因子 并发症发生率 

分 类 号：R57[医药卫生—消化系统]