经全乳晕入路全腔镜下行甲状腺良性肿瘤手术的临床效果及安全性探讨  

Clinical Effect and Safety of Total Endoscopic Thyroidectomy Via Areola Approach for Benign Thyroid Tumors

作　　者：马留学 李鑫 陈治川 MA Liuxue;LI Xin;CHEN Zhichuan(Department of General Surgery,Liangzhou Hospital of Wuwei City,Wuwei 733000,Gansu,China)

机构地区：[1]武威市凉州医院普外科,甘肃武威733000

出　　处：《中外医疗》2024年第23期1-4,12,共5页China & Foreign Medical Treatment

基　　金：武威市市列科技计划项目任务书(WW2101180)。

摘　　要：目的探究经全乳晕入路全腔镜下行甲状腺良性肿瘤手术的临床效果及安全性。方法随机选取2021年6月—2023年6月武威市凉州医院普外科收治的100例甲状腺良性肿瘤患者为研究对象,根据不同治疗方法分为两组,每组50例。观察组经全乳晕入路全腔镜下手术,对照组采用开放手术方式进行治疗。比较两组手术指标、应激激素水平、甲状腺激素水平、并发症发生率。结果观察组的手术时间、住院时间均短于对照组,术后1 d引流量、出血量均少于对照组,差异有统计学意义(P均<0.05)。观察组并发症发生率2.00%(1/50)低于对照组的20.00%(10/50),差异有统计学意义(χ^(2)=8.274,P<0.05)。术后12 h,观察组皮质醇为(234.25±5.71)mg/L、去甲肾上腺素为(285.96±5.71)pmol/L、促肾上腺皮质激素为(1622.63±25.96)pmol/L,均低于对照组的(270.63±5.33)mg/L、(350.63±6.07)pmol/L、(1898.36±26.11)pmol/L,差异有统计学意义(t=32.933、54.873、52.953,P均<0.05)。术后12 h,两组甲状腺激素水平对比,差异无统计学意义(P>0.05)。结论经全乳晕入路全腔镜下行甲状腺良性肿瘤手术的临床疗效十分显著,且具有较高的安全性。Objective To explore the clinical efficacy and safety of total endoscopic thyroidectomy for benign thyroid tumors through the total areola approach.Methods A total of 100 patients with benign thyroid tumors admitted to the Department of General Surgery in Liangzhou Hospital of Wuwei City from June 2021 to June 2023 were randomly se-lected as the research objects.They were divided into two groups by different treatment methods,with 50 cases in each group.The observation group was treated with total endoscopic thyroidectomy through the whole areola approach,and the control group was treated with open surgery.The surgical indicators,stress hormone levels,thyroid hormone levels,and complication rates were compared between the two groups.Results The operation time and hospitalization time of the observation group were shorter than those of the control group,and the drainage volume and bleeding volume at 1 d after operation were less than those of the control group,the differences were statistically significant(all P<0.05).The incidence of complications in the observation group was 2.00%(1/50)lower than that in the control group 20.00%(10/50),the difference was statistically significant(χ^(2)=8.274,P<0.05).12 hours after surgery,cortisol was(234.25±5.71)mg/L,norepinephrine was(285.96±5.71)pmol/L and adrenocorticotropic hormone was(1622.63±25.96)pmol/L in the observation group,which were lower than those in the control group(270.63±5.33)mg/L,(350.63±6.07)pmol/L,(1898.36±26.11)pmol/L,the differences were statistically significant(t=32.933,54.873,52.953,all P<0.05).At 12 h after operation,there was no significant difference in thyroid hormone levels between the two groups(P>0.05).Conclu-sion The clinical effect of the benign thyroid tumor surgery by the whole areola approach is significant and has high safety.

关 键 词：甲状腺良性肿瘤 经全乳晕入路 全腔镜下手术 临床效果 安全性 

分 类 号：R736.1[医药卫生—肿瘤]