抑郁症与甲状腺激素的研究进展  

Research progress on depression and thyroid hormones

作　　者：廖小梅[1] LIAO Xiaomei(West China Hospital,Sichuan University,Chengdu 610041,China)

机构地区：[1]四川大学华西医院,四川成都610041

出　　处：《中国实用神经疾病杂志》2024年第10期1316-1320,共5页Chinese Journal of Practical Nervous Diseases

基　　金：四川省科技计划项目(编号:2023YFS0290)。

摘　　要：抑郁症发病机制十分复杂,至今尚无明确定论,其中神经内分泌假说认为,抑郁症发病与人体下丘脑-垂体-肾上腺轴或甲状腺轴功能异常有关。近年来,随着抑郁症与神经内分泌功能之间的关系被临床研究证实,神经内分泌假说逐渐被认可,然而这些研究结论之间仍存在许多矛盾与争议。为探究抑郁症与甲状腺激素的相关性及相关机制,本文将目前国内外抑郁症的治疗与甲状腺激素的相关研究作一综述。The pathogenesis of depression is very complex,and there is no clear conclusion so far.The neuroendocrine hypothesis holds that the pathogenesis of depression is related to the dysfunction of hypothalamus-pituitary-adrenal axis or thyroid axis.In recent years,the relationship between depression and neuroendocrine function has been confirmed by a large number of clinical studies,and the neuroendocrine hypothesis has been gradually recognized by many scholars.However,there are still many contradictions and disputes between these research conclusions.In order to investigate the relationship between depression therapy and thyroid hormones and related mechanisms,this paper reviews and discusses the current researches on the association between depression therapy and thyroid hormone at home and abroad.

关 键 词：抑郁症 甲状腺激素 神经内分泌 甲状腺功能紊乱 

分 类 号：R749.4[医药卫生—神经病学与精神病学]