吲哚美辛栓联合氨酚羟考酮片用于子宫动脉栓塞术后镇痛效果  

Effect of indomethacin suppository combined with oxycodone and acetaminophen tablet used for analgesia after uterine artery embolization

作　　者：宋福婷 聂琦 李小珍 张万华 SONG Futing;NIE Qi;LI Xiaozhen;ZHANG Wanhua(The 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army,Lanzhou,Gansu Prov-ince,730050)

机构地区：[1]中国人民解放军联勤保障部队第九四〇医院,兰州730050

出　　处：《中国计划生育学杂志》2024年第9期2052-2056,共5页Chinese Journal of Family Planning

摘　　要：目的:探讨行子宫动脉栓塞术(UAE)患者术后镇痛中应用吲哚美辛栓联合氨酚羟考酮片的临床效果。方法:选取2019年1月-2024年1月本院诊治的行UAE患者80例,随机数字分组标准分为两组各40例,术后对照组采取氨酚羟考酮片镇痛,联合组采取氨酚羟考酮片联合吲哚美辛栓镇痛,对比两组术后疼痛程度[视觉模拟评分法(VAS)]评分、生命体征[舒张压(DBP)、脉率(PR)、收缩压(SBP)]、舒适程度[布氏舒适评分法(BCS)]评分、不良反应、术后恢复情况。结果:术后3 h、6 h、12 h、24 h、48 h时,两组VAS评分均较术后即刻降低,两组BCS评分均较术后即刻升高,且联合组各时点VAS评分均低于对照组、BCS评分均高于对照组;术后6 h、12 h,两组DBP、PR、SBP均较术后即刻降低,且联合组低于对照组(均P<0.05)。两组药物不良反应率(5.0%、12.5%)无差异(P>0.05)。联合组术后首次下床活动时间(19.52±3.25 h)、术后住院时间(10.65±3.93 d)均短于对照组(25.26±3.46 h、14.64±3.85 d)(均P<0.05)。结论:吲哚美辛栓联合氨酚羟考酮片用于UAE术后镇痛效果显著,且患者舒适度高,术后恢复更快。Objective:To investigate the clinical effect of indomethacin suppository combined with oxycodone and acetaminophen tablet for postoperative analgesia of patients who had undergone uterine artery embolization(UAE).Methods:80 patients with UAE who received treatment in the hospital were selected and were divided into two groups according to the random number grouping criteria(40 cases in each group)from January 2019 to January 2024.The patients in the control group were treated with oxycodone and acetaminophen tablet for the postoperative analgesia,while the patients in the study group were treated with indomethacin suppository combined with oxycodone and acetaminophen tablet for the postoperative analgesia.The postoperative pain score evaluated by visual analogue scale(VAS),the values of vital signs,such as diastolic blood pressure(DBP),pulse rate(PR)and systolic blood pressure(SBP),the comfort degree evaluated by Bruggrmann comfort score(BCS),the adverse reactions rate and the postoperative recovery status of the patients were compared between the two groups.Results:The VAS score of the patients in the two group at postoperative 3h,6h,12h,24h,or 48h was significantly lower than that of the patients at postoperative immediately,and which of the patients in the study group at different time point was significantly lower than that of the patients in the control group.The BCS score of the patients in the two group at postoperative 3h,6h,12h,24h,or 48h was significantly higher than that of the patients at postoperative immediately,and which of the patients in the study group at different time point was significantly higher than that of the patients in the control group.The values of DBP,PR and SBP of the patients in the two group at postoperative 6hor 12hwere significantly lower than those of the patients at postoperative immediately,and which of the patients in the study group at postoperative 6hor 12hwere significantly lower than those of the patients in the control group(all P<0.05).There was no significant differe

关 键 词：子宫动脉栓塞术 术后镇痛 吲哚美辛栓 氨酚羟考酮片 效果 不良反应 

分 类 号：R737.33[医药卫生—肿瘤]