香草醛取代的苝酰亚胺荧光探针的制备及对Pb^(2+)的识别  

Preparation of Vanillin-substituted Perylenediimide Fluorescent Probes and Identification of Pb^(2+)

作　　者：郭学思 沈阿宁 康子林 单浩杨 马雪珂 李凌宇 李子龙 付丽娜[1] Guo Xuesi;Shen Aning;Kang Zilin;Shan Haoyang;Ma Xueke;Li Lingyu;Li Zilong;Fu Lina(School of Midicine,Huanghe Science&Technology College,Zhengzhou 450063,China)

机构地区：[1]黄河科技学院医学院,河南郑州450063

出　　处：《广东化工》2024年第17期43-45,共3页Guangdong Chemical Industry

基　　金：国家级大学生创新项目(202311834034);郑州市大学生创业项目(郑教高函[2023]851号);第二批河南省专创融合特色示范课程《药物化学》(教办高[2024]2号);河南省民办教育专业建设资助项目(药物制剂ZLG202202);河南省专业学位研究生精品教学案例项目(YJS2024AL148);河南省高等教育教学改革研究与实践项目(2024SJGLX0579);河南省高等教育教学改革研究与实践项目(2023SJGLX379Y);黄河科技学院课程思政示范课建设项目(kg2022sz18);黄河科技学院创新创业教育示范课建设项目(JCXK202213);黄河科技学院项目化教学课程(kg20231xm67)。

摘　　要：将苝酰亚胺衍生物作为荧光团,以苝四酸酐和香草醛为原料,设计并合成了一种高效、有特定反应性能的新型苝酰亚胺类Pb^(2+)荧光探针N,N-双香草醛基-1,6,7,12-四氯-3,4:9,10-苝二酰亚胺(PDI-VBD)。通过质谱、核磁等检测手段对探针分子PDI-VBD的结构进行表征,利用紫外-可见吸收光谱和荧光光谱法探究了探针PDI-VBD对Pb^(2+)的荧光识别性能。光谱分析研究结果显示,在NMP/H_(2)O溶液体系中,探针分子PDI-VBD对Pb^(2+)显示出较强的选择性识别能力和较高的灵敏度,即苝酰亚胺衍生物PDI-VBD自身的荧光较弱,但与Pb^(2+)结合之后,生成了具有较强荧光的配位化合物。金属离子共存实验证明此荧光探针对Pb^(2+)选择性高,且不受其他金属离子干扰。结果表明,香草醛取代的苝酰亚胺衍生物PDI-VBD是一种新型Pb^(2+)荧光探针,选择性好、灵敏度高,可用于实际水样、食品及环境中重金属Pb^(2+)的检测。A novel perylenediimide Pb^(2+)fluorescent probe N,N-diheraldehyde-1,6,7,12-tetrachloro-3,4:9,10-perylenediimide(PDI-VBD)was designed and synthesizedthrough using perylenediimides as fluorescent groups,using perylene tetracarboxylic anhydride and vanillin as raw materials.The structure of probe PDI-VBD was characterized by MS and NMR.The fluorescence recognition performance of probe PDI-VBD for Pb^(2+)was investigated by UV absorption and fluorescence spectroscopy.The results of spectral analysis show that the probe PDI-VBD shows strong selective recognition ability and high sensitivity to Pb^(2+)in NMP/H_(2)O solution.The perylenediimide derivatives PDI-VBD has weak fluorescence,but after combining with Pb^(2+),it produces a coordination compound with strong fluorescence.Metal ion coexistence experiments show that the fluorescence probe has high selectivity for Pb^(2+)and is not interfered by other metal ions.The results showed that the vanillin-substituted perylenediimide derivative PDI-VBD is a novel Pb^(2+)fluorescent probe with good selectivity and high sensitivity,which can be used for the detection of heavy metal Pb^(2+)in real water samples,food and environment.

关 键 词：香草醛 苝酰亚胺 荧光探针 Pb^(2+) 

分 类 号：G420[文化科学—课程与教学论]