多模态超声及影像组学在绝经期及绝经前期甲状腺乳头状癌颈部淋巴结转移诊断中的应用价值  

Study of the efficacy of multimodal ultrasound in the diagnosis of cervical lymph node metastasis in menopausal and premenopausal patients with papillary thyroid carcinoma

作　　者：李静 郭强 Li Jing;Guo Qiang(Department of Ultrasound,Qingpu Branch of Zhongshan Hospital Affiliated to Fudan University,Qingpu District,Shanghai 201799,China)

机构地区：[1]复旦大学附属中山医院青浦分院超声科,上海201799

出　　处：《实用妇科内分泌电子杂志》2024年第19期95-97,共3页Electronic Journal of Practical Gynecological Endocrinology

基　　金：复旦大学附属中山医院青浦分院科研课题(编号QYM2022-09);青浦区卫生健康委员会科研课题(编号QWJ2023-19)。

摘　　要：目的研究多模态超声及影像组学在绝经期及绝经前期甲状腺乳头状癌(PTC)颈部淋巴结转移诊断中的应用价值。方法选取100例绝经期及绝经前期PTC患者为研究对象,根据多模态超声检查结果提取结节病灶的影像特征,通过患者发生颈部淋巴结转移的独立危险因素分析构建临床预测模型,提取多模态影像学特征构建多模态超声影像组学预测模型。结果多灶结节、被膜侵犯、微钙化、结节增强方式是患者颈部淋巴结转移的独立危险因素(P<0.05)。临床预测模型预测患者颈部淋巴结转移的敏感性为77.50%,特异性为86.67%,多模态影像组学模型依次为92.43%、88.57%。结论多模态超声影像组学预测模型对绝经期及绝经前期PTC患者颈部淋巴结转移的预测效能高于基于独立危险因素构建的临床预测模型。Objective To investigate the efficacy of multimodal ultrasound in the diagnosis of cervical lymph node metastasis in menopausal and premenopausal patients with papillary thyroid cancer.Methods 100 cases of menopausal and premenopausal PTC patients treated in our hospital were selected as the study objects.The image features of nodular lesions were extracted according to the results of multimodal ultrasound.The clinical prediction model was constructed by independent risk factor analysis,and the multimodal imaging features were extracted to construct the multimodal ultrasonic image omics prediction model.Results Multiple nodules,capsular invasion,microcalcification and nodule enhancement were independent risk factors for cervical lymph node metastasis(P<0.05).The sensitivity and specificity of clinical prediction model for cervical lymph node metastasis were 77.50%and 86.67%respectively,and the multimodal imaging model was 92.43%and 88.57%respectively.Conclusion The value of multimodal ultrasonography in predicting cervical lymph node movement in menopausal and premenopausal PTC patients is higher than that of the prediction framework based on independent risk factors.

关 键 词：多模态超声 影像组学 甲状腺乳头状癌 颈部淋巴结转移 诊断 

分 类 号：R736.1[医药卫生—肿瘤] R445.1[医药卫生—临床医学]