自主神经系统调控在原发性青光眼中的作用及机制  

Role and mechanism of autonomic nervous system regulation in primary glaucoma

作　　者：朱蕾 申晓丽 李安竹 汪建涛 Zhu Lei;Shen Xiaoli;Li Anzhu;Wang Jiantao(Shenzhen Eye Hospital,Shenzhen Eye Institute,Shenzhen Eye Hospital affiliated to Jinan University,School of Optometry,Shenzhen University,Shenzhen 518040,China)

机构地区：[1]深圳市眼科医院,深圳市眼病防治研究所,暨南大学附属深圳眼科医院,深圳大学眼视光学院,深圳518040

出　　处：《中华眼科杂志》2024年第9期780-786,共7页Chinese Journal of Ophthalmology

基　　金：国家自然科学基金(82070961)。

摘　　要：人眼血流、房水生成速率和房水流出通道均受自主神经系统(交感神经和副交感神经)的调控,原发性青光眼患者往往伴有自主神经系统功能异常,而且自主神经系统功能异常有可能促进青光眼患者视功能的进一步损伤。自主神经系统的稳态受到昼夜节律、运动、精神心理以及药物等因素的影响,既往研究发现,有氧运动、瑜伽呼吸法、冥想等活动可促进自主神经系统稳态的恢复,且有降低眼压的作用。但是,调节自主神经系统的活动可成为原发性青光眼有效的辅助治疗方法仍需要更多证据证明。本文就自主神经系统调控在原发性青光眼中的作用及机制作一综述。The regulation of blood flow in the human eye,aqueous humor production,and the outflow channels of aqueous humor are all controlled by the autonomic nervous system(ANS),encompassing both sympathetic and parasympathetic nerves.Patients with primary glaucoma often exhibit autonomic nervous system dysfunctions,which may exacerbate visual impairment.The homeostasis of the autonomic nervous system is influenced by circadian rhythms,physical exercise,emotional states,medications,and other factors.Previous studies have indicated that activities such as aerobic exercise,yoga breathing,and meditation can promote the restoration of autonomic nervous system balance,thereby reducing intraocular pressure.However,further evidence is required to substantiate the efficacy of ANS activity regulation as an effective adjunct therapy for primary glaucoma.This review examines the role and mechanisms of autonomic nervous system regulation in the context of primary glaucoma.

关 键 词：青光眼 自主神经系统 自主神经系统疾病 

分 类 号：R775.2[医药卫生—眼科]