基于绿色化学的烯烃Meerwein水合反应创新综合实验设计  

Design of Olefin Meerwein Hydration Reaction Experiment Based on Green Chemistry

作　　者：韩金娥 钮腾飞 HAN Jin-E;NIU Teng-Fei(College of Life Sciences and Health Engineering,Jiangnan University,Wuxi 214122,China;College of Chemical and Material Engineering,Jiangnan University,Wuxi 214122,China)

机构地区：[1]江南大学生命科学与健康工程学院,江苏无锡214122 [2]江南大学化学与材料工程学院,江苏无锡214122

出　　处：《化学教育（中英文）》2024年第18期61-68,共8页Chinese Journal of Chemical Education

基　　金：国家级一流本科专业建设项目;江苏省高等教育教改立项研究课题(2023JSJG342);江苏省卓越工程师教育培养计划2.0专业建设点;江南大学本科教育教学改革项目(JG240129)。

摘　　要：聚焦前沿热点,实施科教融合,基于绿色化学理念,设计了烯烃Meerwein水合反应综合实验。该实验引入光催化合成技术,采用自制、可循环利用的催化剂,以水作为溶剂,在清洁可再生的太阳光照射下进行烯烃Meerwein水合反应,并探究合成了一系列1,2-二苯乙醇衍生物。本实验包含催化剂的制备与表征,产物的合成与表征,合成反应条件探索,催化剂循环利用实验,以及底物的适应性考察等,内容丰富有层次,涉及多学科知识交叉与融合,不仅提升学生的综合知识运用能力,还激发学生的科学探究兴趣和创新精神。Focusing on the frontier hot spots,implementing the integration of science and education,based on the concept of green chemistry,the comprehensive innovation experiment of olefin Meerwein hydration reaction was designed.In this experiment,photocatalytic synthesis technology was introduced,and a series of 1,2-diphenyl ethanol derivatives were synthesized through alkene Meerwein hydration reaction using the self-made,recyclable catalyst,water as solvent under clean and renewable sunlight.This experiment includes preparation and characterization of the catalyst,synthesis and characterization of products,optimization of reaction conditions,catalyst recycling experiment,and adaptation investigation of substrates.The experiment content is rich and multi-level,involving the cross and fusion of multidisciplinary knowledge,which not only improves students'comprehensive knowledge application,but also stimulates students'interest in scientific inquiry and innovative spirit.

关 键 词：绿色化学 Meerwein水合反应 光催化 可循环催化剂 

分 类 号：G642.423[文化科学—高等教育学] O621.25-4[文化科学—教育学]