派克斯根管充填联合半导体激光治疗牙周牙髓病患者的疗效评价  

Evaluation of the Efficacy of Pax Root Canal Filling Combined with Semiconductor Laser in the Treatment of Periodontal Pulp Disease

作　　者：张丽丽 张伟伟 蒋焕 Zhang Lili;Zhang Weiwei;Jiang Huan(Department of Stomatology,Xuchang People’s Hospital,Xuchang,Henan,461000,China)

机构地区：[1]许昌市人民医院口腔科,河南许昌461000

出　　处：《黑龙江医学》2024年第18期2183-2186,共4页Heilongjiang Medical Journal

摘　　要：目的:评价派克斯根管充填联合半导体激光治疗牙周牙髓病患者的疗效情况。方法:选取2020年12月—2021年9月许昌市人民医院收治的108例牙周牙髓病患者作为研究对象,采用随机数表法将患者分为对照组和观察组,每组各54例。对照组采用比塔派克斯根管充填治疗,观察组在对照组的基础上加用半导体激光治疗。比较两组患者临床疗效、治疗前、治疗后1个月牙周健康指标、咀嚼效能、龈沟液骨代谢指标、龈沟液超敏C反应蛋白(hs-CRP)、白细胞介素-1β(IL-1β)、钙结合蛋白S100A12(S100A12)、音猬因子(Shh)蛋白水平。结果:观察组临床总有效率高于对照组,差异有统计学意义(χ^(2)=4.364,P<0.05);治疗后1个月,观察组牙龈指数(GI)、牙周探诊深度(PD)、改良出血指数(mBI)、临床附着水平(CAL)降低幅度大于对照组,差异有统计学意义(t=5.024、15.985、5.658、7.532,P<0.05);治疗后1个月,观察组咀嚼效率、咬合力较对照组明显升高,差异有统计学意义(t=5.800、9.146,P<0.05);治疗后1个月,各组龈沟液骨钙素(BGP)、碱性磷酸酶(ALP)、骨保护(OPG)、Ⅰ型前胶原N端前肽(PⅠNP)水平明显升高,差异有统计学意义(t=5.669、7.278、3.607、7.812,P<0.05);治疗后1个月,观察组龈沟液hs-CRP、IL-1β、S100A12、Shh蛋白水平较对照组低,差异有统计学意义(t=6.463、14.593、5.902、7.994,P<0.05)。结论:在比塔派克斯根管充填治疗牙周牙髓病患者基础上,加用半导体激光治疗疗效显著,可有效改善牙周健康及咀嚼效能,调节龈沟液骨代谢指标,促进患者病情恢复。Objective:To investigate the efficacy of Pax root canal filling combined with semiconductor laser in the treatment of periodontal pulp disease.Methods:A total of 108 patients with periodontal pulp disease admitted to the hospital from December 2020 to September 2021 were selected as the research objects.The patients were divided into control group and observation group by random number table method,with 54 cases in each group.The control group was treated with bitapexes root canal filling,and the observation group was treated with semiconductor laser.The clinical efficacy,periodontal health indexes before and after treatment,masticatory efficacy,gingival crevicle fluid bone metabolism indexes,proterminal peptide(PⅠNP),gingival crevicle fluid hypersensitive C-reactive protein(hs-CRP),interleukin-1β(IL-1β),calcium-binding protein S100A12(S100A12)and sonic hedgehog(Shh)protein were compared between the two groups.Results:The total effective rate of the observation group was higher than that of the control group(χ^(2)=4.364,P<0.05).GI,PD,mBI and CAL in observation group were lower than those in control group one month after treatment(t=5.024,15.985,5.658,7.532;P<0.05).One month after treatment,the masticatory efficiency and biting force of observation group were higher than those of control group(t=5.800,9.146;P<0.05).One month after treatment,the levels of BGP,ALP,OPG and PⅠNP in gingival crevicular fluid of observation group were higher than those of control group(t=5.669,7.278,3.607,7.812;P<0.05).One month after treatment,the protein levels of hs-CRP,IL-1β,S100A12 and Shh in gingival crevicular fluid of observation group were lower than those of control group(t=6.463,14.593,5.902,7.994;P<0.05).Conclusion:On the basis of Bitapexus root canal filling treatment for periodontal pulp disease,semiconductor laser treatment is effective.It can effectively improve periodontal health and masticatory efficiency,regulate gingival crevicular fluid bone metabolism index,and promote disease recovery.

关 键 词：派克斯根管充填 半导体激光 牙周牙髓病 疗效 

分 类 号：R781.3[医药卫生—口腔医学]