5例甲状旁腺腺瘤诊治分析  

Analysis of diagnosis and treatment of 5 cases of parathyroid adenoma

作　　者：李政 王丽萍 王念 韩兴发 蒋榕 马志敏 LI Zheng;WANG Liping;WANG Nian;HAN Xingfa;JIANG Rong;MA Zhimin(Endocrinology Department,the Affiliated Suzhou Hospital of Nanjing University Medical School,Suzhou 215153,China)

机构地区：[1]南京大学医学院附属苏州医院内分泌科,江苏苏州215153

出　　处：《临床医学研究与实践》2024年第27期5-8,共4页Clinical Research and Practice

摘　　要：目的 分析5例甲状旁腺腺瘤(PA)患者的疾病特征,以提高临床对该病的诊治能力。方法 回顾性分析2021年1月至2022年7月明确诊断为PA的5例患者的一般资料、临床表现、实验室检查结果、影像学检查结果等。结果 5例患者均为女性,年龄28~67岁。入院时血钙水平[(2.92±0.18)mmol/L]均升高,血磷水平[(0.73±0.12)mmol/L]降低,甲状旁腺激素(PTH)水平[(161.30±68.00)pg/mL]明显升高,维生素D[(11.00±4.60)μg/L]缺乏。患者均为单发甲状旁腺病灶。4例患者于本院行PA切除术,术后PTH、血钙均正常。结论 中老年女性出现口干、乏力症状,合并多发泌尿系结石时,应注意检查血钙,进而检查是否存在PA;甲状旁腺发射型计算机断层扫描仪(ECT)检查为原发性甲状旁腺功能亢进症确诊的有效检查手段。Objective To analyze the genius morbi of 5 patients with parathyroid adenoma(PA)in order to improve clinical diagnosis and treatment ability for this disease.Methods The general data,clinical manifestations,laboratory findings and imaging findings of 5 patients diagnosed with PA from January 2021 to July 2022 were retrospectively analyzed.Results All 5 patients were female,aged 28-67 years.On admission,serum calcium level[(2.92±0.18)mmol/L]increased,serum phosphorus level[(0.73±0.12)mmol/L]decreased,parathyroid hormone(PTH)level[(161.30±68.00)pg/mL]significantly increased,and vitamin D level[(11.00±4.60)μg/L]was deficient.All patients were single parathyroid lesions.Four patients underwent PA resection in our hospital,and PTH and serum calcium were normal after operation.Conclusion Middle-aged and elderly women with dry mouth,fatigue symptoms,combined with multiple urinary calculi,should pay attention to check the blood calcium,and then check whether there is PA;the examination of parathyroid emission computed tomography(ECT)is an effective examination method for the diagnosis of primary hyperparathyroidism.

关 键 词：原发性甲状旁腺功能亢进症 甲状旁腺腺瘤 疾病特征 

分 类 号：R736.2[医药卫生—肿瘤]