阿替卡因肾上腺素与盐酸甲哌卡因在慢性牙髓炎治疗中的应用效果比较  

Comparison of the Effectiveness of the Application of Articaine Epinephrine and Mepivacaine Hydrochloride in the Treatment of Chronic Pulpitis

作　　者：毛良军 Mao Liangjun(Department of Endodontics,Huizhou Stomatological Hospital,Huizhou 516000,Guangdong Province,China)

机构地区：[1]惠州口腔医院牙体牙髓科,广东惠州516000

出　　处：《中外医药研究》2024年第23期75-77,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

基　　金：惠州市科技计划项目(编号:2021WC0106291)。

摘　　要：目的:比较阿替卡因肾上腺素与盐酸甲哌卡因在慢性牙髓炎治疗中的应用效果。方法:选取2021年1月—2022年12月惠州口腔医院牙体牙髓科收治的慢性牙髓炎患者200例为研究对象,随机分为对照组与观察组,各100例。对照组给予盐酸甲哌卡因麻醉,观察组给予阿替卡因肾上腺素麻醉。比较两组麻醉优良率、血流动力学指标水平、不良反应发生率。结果:观察组麻醉优良率高于对照组(P=0.002)。观察组不同时间点舒张压(DBP)、收缩压(SBP)、心率(HR)比较,差异无统计学意义(P>0.05);对照组麻醉后1 min至术后DBP、SBP、HR高于麻醉前(P<0.05)。两组麻醉前DBP、SBP、HR比较,差异无统计学意义(P>0.05);麻醉后1 min至术后,观察组DBP、SBP、HR低于对照组(P<0.05)。观察组不良反应发生率低于对照组(P=0.022)。结论:在牙髓炎治疗中应用阿替卡因肾上腺素的麻醉效果显著,患者生命体征稳定、不良反应发生率低。Objective:To compare the application effect of articaine epinephrine and mepivacaine hydrochloride in the treatment of chronic pulpitis.Methods:Two hundred patients with chronic pulpitis admitted to the Department of Endodontics of Huizhou Stomatological Hospital from January 2021 to December 2022 were selected for the study,and were randomly divided into the control group and the observation group,one hundred cases each.The control group was given mepivacaine hydrochloride anesthesia,and the observation group was given articaine epinephrine anesthesia.Compare the anesthesia excellence rate,hemodynamic index level,and the incidence of adverse reactions in the two groups.Results:The anesthesia excellence rate of the observation group was higher than that of the control group(P=0.002).Comparison of diastolic blood pressure(DBP),systolic blood pressure(SBP),and heart rate(HR)at different time points in the observation group showed no statistically significant difference(P>0.05);DBP,SBP,and HR were higher than those before anesthesia in the control group from 1 min after anesthesia to the postoperative period(P<0.05);comparison of DBP,SBP and HR before anesthesia between the two groups,the difference was not statistically significant(P>0.05);1 min after anesthesia to postoperative,DBP,SBP and HR of the observation group were lower than those of the control group(P<0.05);and the incidence of adverse reactions in the observation group was lower than that of the control group(P=0.022).Conclusion:The anesthetic effect of the application of articaine epinephrine in the treatment of pulpitis was remarkable,and the vital signs of patients were stable and the incidence of adverse reactions was low.

关 键 词：慢性牙髓炎 阿替卡因肾上腺素 盐酸甲哌卡因 

分 类 号：R781.31[医药卫生—口腔医学]