超声造影定量分析技术对乳腺癌浸润程度及病灶可切除性的评估价值  

Value of contrast-enhanced ultrasound quantitative analysis in evaluating the degree of breast cancer invasion and resectable lesion

作　　者：付豪 张亚娟 郭亚兰 Fu Hao;Zhang Yajuan;Guo Yalan(Department of Ultrasound Room,Luohe Hospital of Traditional Chinese Medcine,Henan 462000,China)

机构地区：[1]河南省漯河市中医院彩超室,462000

出　　处：《实用医学影像杂志》2024年第4期281-284,共4页Journal of Practical Medical Imaging

摘　　要：目的 探讨超声造影定量分析技术对乳腺癌浸润程度及可切除性的评估价值,以期为临床制定干预方案提供参考。方法 选取我院2020年8月至2022年8月就诊的乳腺癌患者118例,所有患者入院后均行超声造影检查,比较不同乳腺癌浸润程度患者超声造影定量参数[达峰时间(TTP)、峰值强度(PI)、上升支斜率(WIS)],分析超声造影定量参数与乳腺癌浸润程度相关性,根据临床实际分为手术切除组(64例)与不可手术切除组(54例),比较2组入院时超声造影定量参数,分析超声造影定量参数对乳腺癌病灶可切除性的评估价值。结果 不同浸润程度乳腺癌患者TTP比较:浸润性1级组>浸润性2级组>浸润性3级组;PI、WIS比较:浸润性1级组<浸润性2级组<浸润性3级组(P<0.05);经相关性分析显示,TTP与乳腺癌浸润程度呈负相关,PI、WIS与乳腺癌浸润程度呈正相关(P<0.05);与不可手术切除组比较,手术切除组TTP较高,PI、WIS较低(P<0.05);经受试者工作特征(ROC)曲线分析显示,TTP、PI、WIS对乳腺癌手术可切除性联合评估曲线下面积(AUC)为0.927,大于单一参数;TTP、PI、WIS低水平组不可手术切除风险分别为高水平组的2.803、0.580、0.444倍(P<0.05)。结论超声造影定量分析技术可用于评估乳腺癌浸润程度,为临床评估可切除性提供依据,以制定后续治疗方案。Objective To explore the value of quantitative analysis of contrast-enhanced ultrasound in evaluating the degree of breast cancer invasion and resectable,in order to provide reference for clinical intervention.Methods A total of 118 breast cancer patients in our hospital from August 2020 to August 2022 were selected and underwent contrast-enhanced ultrasound examination after admission.Quantitative parameters of contrast-enhanced ultrasound,including time to peak(TTP),peak intensity(PD),and wash in slope,in patients with dfferent degrees of breast cancer invasion were compared.The correlation between quantitative parameters of contrast-enhanced ultrasound(CEUS)and the degree of breast cancer invasion was analyzed,and the two groups were divided into surgical resection group(n=64)and non-surgical resection group(n=54)according to the actual clinical situation.The quantitative parameters of CEUS were compared between the two groups at admission,and the evaluation value of quantitative parameters of CEUS on the resectable breast cancer lesions was analyzed.Results TTP of patients with different degrees of invasive breast cancer was compared:invasive grade 1 group>invasive grade 2 group>invasive grade 3 group.PI and WIS were compared:infiltrating grade 1 group<infiltrating grade 2 group<infiltrating grade 3 group(P<0.05).Correlation analysis showed that TTP was negatively correlated with the degree of breast cancer invasion,while PI and WIS were positively correlated with the degree of breast cancer invasion(P<0.05).TTP,PI,and WIS in the surgical resection group were higher than in the non-surgical resection group(P<0.05).Receiver operator characteristic curve(ROC)analysis showed that the area under the curve(AUC)of the combined evaluation of TTP,PI,and WIS for breast cancer resection was 0.927,greater than that of a single parameter.The risk of inoperable resection in low TTP,PI,and WIS groups was 2.803,0.580,and 0.444 times of that in high TTP,PI,and WIS groups,respectively(P<0.05).Conclusion Quantitative analysis

关 键 词：超声心动描记术 乳腺肿瘤 肿瘤浸润 病灶感染 

分 类 号：R737.9[医药卫生—肿瘤] R445.1[医药卫生—临床医学]