植入支架治疗特发性颅内高压症合并静脉窦狭窄  

Stent implantation for treating idiopathic intracranial hypertension complicated with venous sinus stenosis

作　　者：徐振 何浩 许莺歌 包雯颍 张松[1] 朱明[1] 吴垠垠 闫磊[1] 水少锋[1] XU Zhen;HE Hao;XU Yingge;BAO Wenying;ZHANG Song;ZHU Ming;WU Yinyin;YAN Lei;SHUI Shaofeng(Department of Interventional Radiology,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China)

机构地区：[1]郑州大学第一附属医院放射介入科,河南郑州450052

出　　处：《中国介入影像与治疗学》2024年第9期513-516,共4页Chinese Journal of Interventional Imaging and Therapy

摘　　要：目的观察植入支架治疗特发性颅内高压症(IIH)合并静脉窦狭窄(VSS)的价值。方法回顾性分析54例接受植入支架治疗的IIH合并VSS患者资料,比较治疗前、后视乳头水肿分级、腰椎穿刺开口压力(LP-OP)及静脉窦跨狭窄段压力梯度(ΔP),记录随访期间症状改善情况及治疗相关并发症。结果对54例共成功植入60枚支架。治疗前视乳头水肿分级为3(3,3)、LP-OP为(391.39±92.62)mmH_(2)O、ΔP为18.50(15.00,25.00)mmHg,治疗后依次降为1(0,1)、(208.80±62.31)mmH_(2)O及1.25(0.88,2.55)mmHg,差异均有统计学意义(P均<0.001)。治疗后54例临床症状均改善,30例(30/37,81.08%)头痛、38例(38/45,84.44%)视乳头水肿、41例(41/45,91.11%)视觉障碍、8例(8/10,80.00%)外展神经麻痹及9例(9/10,90.00%)耳鸣症状消失。4例(4/54,7.41%)出现治疗相关并发症,经干预后均好转。结论植入支架治疗IIH合并VSS效果好且安全。Objective To observe the value of stent implantation for treating idiopathic intracranial hypertension(IIH)complicated with venous sinus stenosis(VSS).Methods Data of 54 patients with IIH complicated with VSS who underwent stent implantation were retrospectively analyzed.The papillary edema grade,lumbar puncture-opening pressure(LP-OP)and trans-stenotic pressure gradient of venous sinus(ΔP)before and after stent implantation were compared,and the symptom improvement and treatment-related complications during the follow-up period were recorded.Results Totally 60 stents were successfully implanted in 54 patients.Before stent implantation,the papillary edema grade was 3(3,3),LP-OP was(391.39±92.62)mmH_(2)O and theΔP was 18.50(15.00,25.00)mmHg,which decreased to 1(0,1),(208.80±62.31)mmH_(2)O and 1.25(0.88,2.55)mmHg after stent implantation,respectively,all with significant differences(all P<0.001).Clinical symptoms improved after stent implantation in all 54 patients.At the end of follow-up,disappearance of headache,papillary edema,visual disorder,abducent nerve paralysis and tinnitus were noticed in 30(30/37,81.08%),38(38/45,84.44%),41(41/45,91.11%),8(8/10,80.00%)and 9 cases(9/10,90.00%),respectively.Treatment-related complications occurred in 4 cases(4/54,7.41%),all improved after intervention.Conclusion Stent implantation was effective and safe for treating IIH complicated with VSS.

关 键 词：颅内高压症 狭窄 支架 

分 类 号：R743[医药卫生—神经病学与精神病学] R815[医药卫生—临床医学]