新生儿肾上腺囊性神经母细胞瘤临床及CT表现  

Clinical and CT features of neonatal adrenal cystic neuroblastoma

作　　者：梁琼鹤[1] 管红梅[1] 蒋维维[2] 盛会雪 王颖 LIANG Qionghe;GUAN Hongmei;JIANG Weiwei;SHENG Huixue;WANG Ying(Department of Radiology,Children's Hospital of Nanjing Medical University,Nanjing 210008,China;Department of Neurosurgery,Children's Hospital of Nanjing Medical University,Nanjing 210008,China)

机构地区：[1]南京医科大学附属儿童医院放射科,江苏南京210008 [2]南京医科大学附属儿童医院新生儿外科,江苏南京210008

出　　处：《中国医学影像技术》2024年第9期1386-1389,共4页Chinese Journal of Medical Imaging Technology

摘　　要：目的观察新生儿肾上腺囊性神经母细胞瘤(CNB)的临床及CT表现。方法回顾性分析经手术病理确诊的8例新生儿肾上腺CNB,记录其临床资料,观察术前全腹CT平扫及增强表现。结果8例中,6例(6/8,75.00%)于胎儿期、2例(2/8,25.00%)于新生儿期经超声检出;均见单侧肾上腺单发病灶,位于左、右侧肾上腺各4个(4/8,50.00%),最大径2.3~6.1 cm、中位最大径4.5 cm。CT显示8个(8/8,100%)病灶均表现为局限性厚壁囊性肿块,其中3个(3/8,37.50%)囊内密度均匀、3个(3/8,37.50%)囊内有分隔、1个(1/8,12.50%)囊内见少许漂浮物、1个(1/8,12.50%)囊内同时存在分隔及漂浮物,均未见钙化;病灶均未见跨越中线、均无血管包绕,7个(7/8,87.50%)边界清晰、1个(1/8,12.50%)边界欠清,均轻度推压周围结构;增强后囊壁及分隔轻度强化。2例累及肝脏。结论新生儿肾上腺CNB多于胎儿期检出,CT主要表现为厚壁囊性肿块,边界清晰,内可有分隔及漂浮物,增强后囊壁及分隔轻度强化;可出现肝脏转移。Objective To observe the clinical and CT features of neonatal adrenal cystic neuroblastoma(CNB).Methods Eight newborns with adrenal CNB confirmed by surgical pathology were retrospectively analyzed.The clinical data were recorded,and the plain and enhancement abdominal CT manifestations were observed.Results Among 8 cases,6(6/8,75.00%)were detected with prenatal ultrasound,while 2(2/8,25.00%)were detected after birth with ultrasound,all with single adrenal grand lesion,located half in left and half in right adrenal gland(each 4/8,50.00%).The maximum diameter of CNB lesion was 2.3—6.1 cm,with the median maximum diameter of 4.5 cm.CT showed all 8 lesions(8/8,100%)presented as single localized adrenal grand thick-walled cystic lesion,among which 3(3/8,37.50%)with uniform density within the cysts,3(3/8,37.50%)with internal septum within the cysts,1(1/8,12.50%)with slight floating debris and the rest 1(1/8,12.50%)with both internal septum and floating debris in the cyst.No calcification,cross the midline nor surround blood vessels were observed.Seven(7/8,87.50%)lesions had clear while 1(1/8,12.50%)had unclear boundaries,all mildly compressed surrounding structures.The capsule wall and internal septum of the cysts slightly enhanced after enhancement.Multiple liver metastases occurred in 2 cases.Conclusion Most neonatal adrenal CNB were detected before delivery,which mainly presented as thick-walled cystic mass with clear boundary,accompanied by septa and floating debris,and the cystic wall and septa slightly enhanced after enhancement,and liver metastasis might occur.

关 键 词：婴儿 新生儿 肾上腺肿瘤 神经母细胞瘤 体层摄影术 X线计算机 

分 类 号：R736.6[医药卫生—肿瘤] R814.42[医药卫生—临床医学]