酒脂复合型急性胰腺炎的临床特点分析  

Analysis of clinical characteristics of alcohol-hyperlipidemia associated acute pancreatitis

作　　者：佟建华 车根 曹曦[2] Tong Jianhua;Che Gen;Cao Xi(Baotou Medical College,Inner Mongolia University of Science and Technology,Baotou 014040,China)

机构地区：[1]内蒙古科技大学包头医学院,内蒙古包头014040 [2]鄂尔多斯市中心医院

出　　处：《华北理工大学学报（医学版）》2024年第5期355-360,共6页Journal of North China University of Science and Technology：Health Sciences Edition

基　　金：内蒙古自治区卫生健康科技计划项目课题(编号:202201594)。

摘　　要：目的 探讨酒脂复合型急性胰腺炎(AHAP)的临床特点。方法 采用回顾性研究方法,收集鄂尔多斯市中心医院2022年1月-2024年5月收治的急性胰腺炎患者161例,根据病因分为酒精性急性胰腺炎(AAP)、高脂血症急性胰腺炎(HLAP)和AHAP组。针对其基线资料,实验室检查指标、严重程度等进行分析与比较。结果 与HLAP组比较,AHAP组男性比例更高(P<0.05);AHAP组合并脂肪肝的比率高于AAP和HLAP组(P<0.05)。AHAP组入院时甘油三酯(TG)、总胆固醇(TC)水平明显高于AAP组和HLAP组(P<0.05),且在住院早期阶段AHAP组重症患者比率更高。通过Logistic回归分析进一步证实,男性、合并脂肪肝和早期阶段重症胰腺炎(SAP)诊断率是AHAP的影响因素。结论 AHAP具有区别于单病因AAP和HLAP的临床特征,其中年男性发病高、合并脂肪肝比率更高,更易发展成为重症。Objective To investigate the clinical characteristics of alcohol-hyperlipidemia associated acute pancreatitis(AHAP).Methods A retrospective study was conducted to collect 161 patients with acute pancreatitis admitted to our hospital from January 2022 to May 2024.Patients were divided into alcoholic acute pancreatitis(AAP),hyperlipidemia-induced acute pancreatitis(HLAP),and AHAP groups based on etiology.Baseline data,laboratory test indicators,and severity were analyzed and compared among the groups.Results Compared with the HLAP group,the AHAP group had a higher male proportion(P<0.05),and a higher rate of concurrent fatty liver than the AAP and HLAP groups(P<0.05).The levels of triglycerides(TG)and total cholesterol(TC)at admission in the AHAP group were significantly higher than those in the AAP and HLAP groups(P<0.05).Additionally,the proportion of severe patients was higher in the early stage of hospitalization in the AHAP group.Further Logistic regression analysis confirmed that male gender,concurrent fatty liver,and early-stage severe acute pancreatitis(SAP)diagnosis rate were influencing factors of AHAP.Conclusion AHAP exhibits distinct clinical features from single-etiology AAP and HLAP,characterized by a higher incidence in middle-aged males,a higher rate of concurrent fatty liver,and a greater tendency to develop into severe pancreatitis.

关 键 词：酒精性胰腺炎 高脂血症性胰腺炎 酒脂复合型胰腺炎 临床特点 

分 类 号：R576[医药卫生—消化系统]