Piecing together aminergic polypharmacology  

作　　者：Blake A.Fordyce Bryan L.Roth 

机构地区：[1]Department of Pharmacology,University of North Carolina Chapel Hill School of Medicine,Chapel Hill,NC,USA

出　　处：《Cell Research》2024年第9期599-600,共2页细胞研究（英文版）

摘　　要：Neuropsychiatric medications are often designed to have affinity for multiple ligand-binding sites across different receptor types to increase therapeutic efficacy. In a recent paper in Cell, Chen and colleagues implement a flexible scaffold-based cheminformatics approach to design bi-target therapeutics for dementia-related psychosis.

关 键 词：MEDICATION efficacy. THERAPEUTIC 

分 类 号：R96[医药卫生—药理学]