利普刀结合阴道镜治疗宫颈轻度上皮内瘤变的效果及对血清肿瘤坏死因子-α、白细胞介素-6的影响  

The Effect of Lip Knife Combined with Colposcopy in the Treatment of Mild Cervical Intraepithelial Neoplasia and Its Effect on Serum TNF-α,the Impact of IL-6

作　　者：郑雪琴 ZHENG Xue-qin(Jinxian County Traditional Chinese Medicine Hospital,Jiangxi Nanchang 331700)

机构地区：[1]进贤县中医院,江西南昌331700

出　　处：《中国医疗器械信息》2024年第17期108-110,共3页China Medical Device Information

摘　　要：目的:观察并讨论利普刀结合阴道镜在治疗宫颈轻度上皮内瘤变的效果以及对血清肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)的影响。方法:2020年1月~2022年12月从本院抽取40例宫颈轻度上皮内瘤变患者,采用数字随机法分为观察组、对照组,各20例。对照组患者采用冷刀宫颈锥切术进行治疗,观察组患者采用利普刀结合阴道镜治疗。比较两组患者的血清TNF-α、IL-6、术后并发症以及术后病灶残留率。结果:观察组患者血清TNF-α、IL-6比对照组更低,差异有统计学意义(P<0.05);观察组术后并发症发生率低于对照组患者,差异有统计学意义(P<0.05);观察组患者的术后病灶残留率远比对照组低,差异有统计学意义(P<0.05)。结论:利普刀结合阴道镜治疗宫颈轻度上皮内瘤变临床效果显著,患者的血清TNF-α、IL-6明显改善,术后并发症以及术后病灶残留较少。Objective:To observe and discuss the effect of lip knife+colposcope in the treatment of mild cervical intraepithelial neoplasia and its effects on serum TNF-αand IL-6.Methods:From January 2020 to December 2022,40 patients with mild cervical intraepithelial neoplasia were selected from our hospital and randomly divided into an observation group and a control group,with 20 patients in each group.The conventional group patients were treated with cold knife cervical conization,while the observation group patients were treated with Lip knife combined with colposcopy.Compare the serum levels of TNF-α,IL-6,postoperative complications,and residual lesion rates between two groups of patients.Results:The serum TNF-αand IL-6 were much lower than the observation group,and the difference was statistically significant(P<0.05);The rate of postoperative complications was lower than that of patients in the observation group,and the difference was statistically significant(P<0.05);The residual rate of patients was much lower than the conventional group,and the difference was statistically significant(P<0.05).Conclusion:He combined with colposcopy had significant clinical effect on cervical mild intraepithelial neoplasia,and his serum TNF-αand IL-6 were significantly improved,with less postoperative complications and postoperative lesions.

关 键 词：宫颈轻度上皮内瘤变 利普刀 阴道镜 血清肿瘤坏死因子-Α 血清白细胞介素-6 

分 类 号：R737.33[医药卫生—肿瘤]