细菌性阴道病实验室诊断方法研究进展  

Progress of research on methods of laboratory diagnosis of bacterial vaginosis

作　　者：邓通洋 陈雪茄 DENG Tong-yang;CHEN Xue-jia(Tongde Hospital of Zhejiang Province,Hangzhou,Zhejiang 310000,China;不详)

机构地区：[1]浙江省立同德医院检验科,浙江杭州310000 [2]杭州市中医院妇产科,浙江杭州310000

出　　处：《中华医院感染学杂志》2024年第18期2876-2880,共5页Chinese Journal of Nosocomiology

基　　金：浙江省自然科学基金基础公益项目(LGC22H200014)。

摘　　要：细菌性阴道病(BV)是妇科最常见疾病之一,与早产、流产、不孕不育、胎膜早破、新生儿感染和盆腔炎密切相关,易复发,且很多患者临床症状较轻或表现为无症状,因此临床诊断主要依靠实验室检查。目前实验室主要的诊断方法有依赖形态学的Nugent评分、Amsel法、Hay-Ison标准,还有干化学检测法、分子生物学方法以及各种组学方法,但还没有一种方法能非常灵敏和准确的诊断BV,尤其是一些新方法诊断标志物的选择还尚不统一,本文旨在阐述以上各种BV诊断方法的优缺点和适用性,并阐述其最新研究进展。Bacterial vaginosis is one of the most common gynecologic diseases and is closely related to premature birth,abortion,infertility,premature rupture of membranes,neonatal infection and pelvic inflammation.It is easy to relapse,and some patients were presented with mild clinical symptoms or were asymptomatic,so the clinical diagnosis mainly depends on laboratory examination.At present,the major diagnosis methods in clinical laboratories include Nugent score based on morphology,Amsel method,Hay-Ison standard,dry chemical detection,molecular biology method and various omics methods.But none of them could be sensitive and accurate for diagnosis of BV,and the choice of diagnostic markers for some of the methods has not been unified yet.The article focuses on the advantages,disadvantages and applicability of the above methods for diagnosis of BV and elaborates on the latest progress of research on the diagnosis methods.

关 键 词：细菌性阴道病 诊断方法 诊断标志物 临床诊断 实验室检查 

分 类 号：R-331[医药卫生]