中国中老年人生活自理能力和衰弱的关系:抑郁起中介作用  

Relationship between self-care and frailty in Chinese middle-aged and older adults:Depression plays a mediating role

作　　者：崔冰炎 陈晨 马润州 郑美洁[3] 刘文秀 李伟[3] 李贤[3] CUI Bing-yan;CHEN Chen;MA Run-zhou;ZHENG Mei-jie;LIU Wen-xiu;LI Wei;LI Xian(College of Nursing,Chengde Medical College,Chengde,Hebei 067000,China;不详)

机构地区：[1]承德医学院护理学院,河北承德067000 [2]河北医科大学研究生学院 [3]河北省人民医院

出　　处：《现代预防医学》2024年第18期3442-3448,共7页Modern Preventive Medicine

基　　金：2024年政府资助临床医学优秀人才培养项目(ZF2024006);河北省2024年度医学科学研究课题计划项目(20240083)。

摘　　要：目的 探讨抑郁在生活自理能力和衰弱之间的中介作用。方法 基于中国健康与养老追踪调查数据,采用Pearson相关分析、线性回归模型和Bootstrap重复抽样法分析生活自理能力、抑郁和衰弱间的关系和中介效应。结果 共纳入了1 554名年龄在45岁以上的中老年人,其中衰弱发生率为14.1%,生活自理能力评分为5.9±0.4,抑郁评分为9.4±6.0。生活自理能力和抑郁、衰弱均显著负相关(r=-0.14,r=-0.23,均P<0.001),抑郁和衰弱呈正相关(r=0.34,P<0.0019)。生活自理能力(β=-0.164,P<0.001)和抑郁(β=0.013,P<0.001)是衰弱的影响因素,抑郁在生活自理能力和衰弱之间起部分中介作用,中介效应占比12.17%。结论 抑郁会降低生活自理能力对衰弱的改善作用。Objective To explore the mediating effect of depression between life self-care ability and frailty.Methods Based on data from the China Health and Retirement Longitudinal Study(CHARLS),Pearson correlation analysis,linear regression model and Bootstrap repeated sampling method were used to analyse the relationships and mediating effects between activity of daily living,depression and frailty.Results A total of 1 554 middle-aged and elderly people aged 45 years or older were included.The prevalence of debility was 14.1%,with a self-care score of 5.9±0.4 and a depression score of 9.4±6.0.Activity of daily living was significantly negatively correlated with depression and frailty(r=-0.14,r=-0.23,both P<0.001),and depression and frailty were positively correlated(r=0.34,P< 0.001).Activity of daily living(β=-0.164,P<0.001) and depression(β=0.013,P< 0.001) were influences on frailty,and depression partially mediated the relationship between activity of daily living and frailty,with a mediating effect of 12.17%.Conclusion Depression reduces the ameliorative effect of self-care ability on debility.

关 键 词：生活自理能力 中老年人 衰弱 中介效应 

分 类 号：R749.4[医药卫生—神经病学与精神病学]