乳腺癌乳房水肿MRI研究进展  

Research progress of MRI in breast cancer with breast edema

作　　者：侯鑫宇 杨婷 李军 HOU Xinyu;YANG Ting;LI Jun(Department of Radiology,Yantai Affiliated Hospital of Binzhou Medical University,Yantai 264100,China)

机构地区：[1]滨州医学院烟台附属医院医学影像科,山东烟台264100

出　　处：《分子影像学杂志》2024年第9期997-1002,共6页Journal of Molecular Imaging

基　　金：山东省自然科学基金面上项目(ZR2022MH064)。

摘　　要：乳腺癌严重威胁女性生命健康,乳腺水肿是乳腺癌常见的并发症,近年来有研究表明乳腺水肿能反应乳腺癌患者病情严重程度、预后情况,MRI对水分子敏感,相对于其他成像方式对水肿的显示具有较大优势,引起了国内外学者的关注。本文对近年来围绕基于MRI的乳腺癌乳房水肿研究展开综述,总结乳腺水肿发生机制、水肿区域划分方法、临床应用价值等研究现状,提出现阶段研究中存在基于MRI显示的水肿边界欠清、缺乏乳腺水肿生物代谢研究等局限性,并提出了图像减影技术、MRS及影像组学技术解决当前研究局限性的思路,旨在为乳腺水肿临床应用于乳腺肿瘤定性、评估患者病情进展及治疗效果等方面提供参考,为乳腺水肿精确定位、研究乳腺水肿生物代谢提供新的研究思路。Breast cancer is a serious threat to women's life and health.Breast edema is a common complication of breast cancer.In recent years,studies have shown that breast edema can reflect the severity and prognosis of breast cancer patients.MRI is sensitive to water molecules.Compared with other imaging methods,it has greater advantages in showing edema,which has attracted the attention of scholars at home and abroad.This article reviews the research on breast cancer breast edema based on MRI in recent years,summarizing the current status of studies on mechanisms of edema occurrence,methods for delineating edema regions,and clinical application values.It identifies limitations in current research,such as unclear delineation of edema borders on MRI and lack of studies on the biological metabolism of breast edema.Proposed solutions include advanced imaging techniques like image subtraction,MRS,and radiomics to address these limitations.This study aims to provide insights into the clinical application of breast edema for qualitative assessment of breast tumors,evaluation of disease progression,and treatment effectiveness.Additionally,it proposes new research directions for precise localization of breast edema and investigation into its biological metabolism.

关 键 词：乳腺癌 乳房水肿 磁共振成像 

分 类 号：R737.9[医药卫生—肿瘤] R445.2[医药卫生—临床医学]