云南元江诺丽果汁对正常大鼠血压与糖尿病模型小鼠血糖的影响  

Effects of Yunnan Yuanjiang Noni Juice on Blood Pressure of Normal Rats and Blood Sugar of Diabetes Model Mice

作　　者：杜鹏鹏 王建昭 蓝增全 王灿[3] 吴田[1] DU Pengpeng;WANG Jianzhao;LAN Zengquan;WANG Can;WU Tian(College of Landscape Architecture and Horticulture Sciences,Southwest Forestry University,Kunming,Yunnan 650224,China;Institute of Green Development of Southwest Forestry University,Kunming,Yunnan 650224,China;Spice and Beverage Research Institute,Chinese Academy of Tropical Agricultural Sciences,Wanning,Hainan 571533,China)

机构地区：[1]西南林业大学园林园艺学院,云南昆明650224 [2]西南林业大学绿色发展研究院,云南昆明650224 [3]中国热带农业科学院香料饮料研究所,海南万宁571533

出　　处：《热带作物学报》2024年第9期1958-1965,共8页Chinese Journal of Tropical Crops

基　　金：国家林业和草原局项目([2019]27)。

摘　　要：为了探究云南元江诺丽果汁与其他种类诺丽果汁对正常大鼠血压与糖尿病模型小鼠血糖的影响,以正常大鼠和糖尿病模型小鼠为研究对象,观察试验前后正常大鼠血压和糖尿病模型小鼠血糖的变化。正常大鼠麻醉后经十二指肠灌注药或果汁,采用直接测压法测定血压,读取试验前后的血压值并进行数据分析;采用腹腔注射四氧嘧啶建立糖尿病小鼠模型,并分别给予造模成功的小鼠相对应的药物或果汁,每日给药或果汁1次,连续给药或果汁9 d,并在第10天采集小鼠血液测定其空腹血糖数值进行研究对比分析。分析大鼠血压发现,云南元江高剂量组在注射云南元江诺丽果汁前后血压值无显著差异;中剂量组在注射90 min前后血压值差异极显著;低剂量组在注射240 min前后血压值差异显著;中剂量组降血压效果最佳。分析糖尿病模型小鼠血糖发现,注射云南元江诺丽果汁的低、中、高3个剂量组均可不同程度地降低血糖,且低剂量组的降血糖效果最佳;大溪地诺丽果汁降糖率为0.00%。云南元江诺丽果汁具有降血糖和降血压的双重功效,且低剂量组降血糖的效果最显著;诺丽由美国夏威夷引种至云南西双版纳和元江,对其降血糖的功效并无显著影响。Normal rats and diabetes model mice were used to explore the effects of Yunnan Yuanjiang noni juice and other noni juice on blood pressure of normal rats and blood sugar of diabetes model mice.The changes of blood pressure in normal rats and blood sugar in diabetes model mice were observed before and after the test.After anesthesia in normal rats,medication or fruit juice was infused into the duodenum,using direct pressure measurement method to measure blood pressure,reading blood pressure values before and after the experiment and conducting data analysis.The model of diabetes mice was established by intraperitoneal injection of alloxan,and the successful mice were given corresponding drugs or juice,continuous administration or juice for nine days.Mouse blood was collected on the 10th day to measure the fasting blood glucose values for comparative analysis.As the analysis of rat blood pressure revealed,there was no significant difference in blood pressure values between the high dose group of Yunnan Yuanjiang noni juice before and after injection;there was a very significant difference in blood pressure values before and after 90 minutes of injection in the medium dose group;there was a significant difference in blood pressure values between the low dose group before and after 240 minutes of injection;the medium dose group had the best blood pressure lowering effect.Analysis of blood sugar in diabetes model mice found that the low,medium and high dose groups of Yunnan Yuanjiang noni juice could reduce blood sugar to varying degrees,and the low-dose group had the best hypoglycemic effect,the hypoglycemic rate of Tahiti noni juice was 0.00%.Yunnan Yuanjiang noni juice has the dual effect of lowering blood sugar and blood pressure,and the low dose group has the best effect of reducing blood sugar.Noni introduced from Hawaii to Xishuangbanna,Yunnan and Yuanjiang,Yunnan has no significant effect on its blood sugar lowering effect.

关 键 词：诺丽果汁 辅助药物 降血糖功效 降血压功效 

分 类 号：TS201.4[轻工技术与工程—食品科学]