以口腔颌面部病变为首发症状的儿童伯基特淋巴瘤1例报告及文献综述  

Burkitt lymphoma manifested by initial oral and maxillofacial lesions:a case report in a child patient and review of related articles

作　　者：武宏 赵文慧 杨小倩 李秀丽 张衍蓉 宋爱梅 Wu Hong;Zhao Wenhui;Yang Xiaoqian;Li Xiuli;Zhang Yanrong;Song Aimei(Dept.of Periodontology,School and Hospital of Stomatology,Cheeloo College of Medicine,Shandong University&Shandong Key Laboratory of Oral Tissue Regeneration&Shandong Engineering Research Center for Dental Materials and Oral Tissue Regeneration&Shandong Provincial Clinical Research Center for Oral Diseases,Jinan 250012,China;Dept.of Stomatology,People’s Hospital of Rizhao,Rizhao 276800,China;Dept.of Hematology,Shandong Provincial Hospital,Jinan 250021,China;Dept.of Orthodontics,Hospital of Stomatology of Yanzhou District of Jining,Jining 272100,China)

机构地区：[1]山东大学齐鲁医学院口腔医学院·口腔医院牙周病科,山东省口腔组织再生重点实验室,口腔生物材料与组织再生山东省工程研究中心,山东省口腔疾病临床医学研究中心,济南250012 [2]日照市人民医院口腔科,日照276800 [3]山东省立医院小儿血液科,济南250021 [4]济宁市兖州区口腔医院正畸科,济宁272100

出　　处：《华西口腔医学杂志》2024年第5期675-682,共8页West China Journal of Stomatology

基　　金：山东省自然科学基金(ZR2020MH184)。

摘　　要：伯基特(Burkitt)淋巴瘤是一种具有高度侵袭性的B细胞淋巴瘤,是增殖最快的人类恶性肿瘤,早期发现具有较高的治疗成功率,晚期则预后较差。本病可发生于儿童和成人,包括地方型(非洲Burkitt淋巴瘤)、散发型和免疫缺陷相关型。散发型Burkitt淋巴瘤最常见的首发部位是腹部器官及淋巴结,以口腔颌面部为首发症状的Burkitt淋巴瘤少见。本文报道1例以面部膨隆、牙痛、牙齿松动等口腔颌面部病变为首发症状的儿童散发型Burkitt淋巴瘤患者,同时对以口腔颌面部病变为首发症状的Burkitt淋巴瘤的发病情况进行文献综述,以期为广大口腔临床医师提供参考,从而对以口腔疾病为表现的Burkitt淋巴瘤患者做到早诊断、早治疗,提高治疗成功率。Burkitt lymphoma is a highly aggressive B-cell lymphoma and the fastest proliferating human malignant tumor.If the disease is found in the early stage,the patient could have a high possibility to be cured successfully,whereas the prognosis is poor in the late stage.Burkitt lymphoma can occur in children and adults,and it is categorized as local(Africa),sporadic,and immunodeficiency associated type.Sporadic Burkitt lymphoma mainly affects children and adolescents,and the most common initial sites are abdominal organs and lymph nodes.Sporadic Burkitt lymphoma manifested by initial oral and maxillofacial lesions is relatively rare.Here,a case of pediatric sporadic Burkitt lymphoma,with oral and maxillofacial lesions as the first symptoms,was reported.The patient was treated in the Department of Periodontology,Shandong University School and Hospital of Stomatology.After timely checkup was provided,the patient was transferred to another hospital and had good results.In this article,an incidence of Burkitt lymphoma,with oral and maxillofacial lesions as the first symptom,was reviewed to provide reference for oral clinicians to achieve early diagnosis and treatment of patients with Burkitt lymphoma with oral diseases and improve the success rate of treatment.

关 键 词：BURKITT淋巴瘤 面部膨隆 牙齿松动 

分 类 号：R739.8[医药卫生—肿瘤]