Are dogs not susceptible to retroviral infections?  

作　　者：Jorge Casseb João Henrique Campos Luciano Rodrigo Lopes 

机构地区：[1]Laboratory of Investigation in Dermatology and Immunodefciencies,Department of Dermatology,University of São Paulo Medical School,São Paulo,SP,Brazil [2]Igen-Institute of Immunogenetics,São Paulo,SP,Brazil [3]Bioinformatics and Biomedical Data Science Division,Health Informatics Department,Universidade Federal de São Paulo–UNIFESP.Rua Botucatu 862,Prédio Leal Prado,térreo,Vila Clementino,CEP 04023-062,São Paulo,SP,Brazil

出　　处：《Animal Diseases》2024年第3期217-223,共7页动物疾病（英文）

基　　金：Fapesp 2014/22827–7;Ministério da Saúde do Brasil;Fundação Faculdade de Medicina and CNPq Grant to JC:301275/2019–0.

摘　　要：Retroviruses have been proven to cause infections and diseases in a series of mammalian hosts but not in dogs.Then,this letter discussed the dog susceptibility to retrovirus infection,encompassing arguments to understand why dogs may have not been infected by retroviruses thus far.The potential resistance of retrovirus in dogs enables this provocative short communication to discuss this question,looking at some evolutive aspects.The lineage of canids has shown,throughout its evolutionary history,a smaller accumulation of retroviruses in canid genomes,classifed as endogenous retroviruses.In this context,the genomes of canids seem to ofer obstacles,which have been evolutionarily conserved,in the face of retroviral infection.

关 键 词：RETROVIRUS DOGS Endogenous retrovirus 

分 类 号：S85[农业科学—兽医学]