Sirius、Lenstar及接触式A超测量白内障眼生物参数的比较  

Comparison of the biometric measurements obtained using Sirius,Lenstar and contact ultrasound A-scan in cataract patients

作　　者：邵颖 黄帅 李晨[1] 刘高勤[1] SHAO Ying;HUANG Shuai;LI Chen;LIU Gaoqin(Department of Ophthalmology,the First Affiliated Hospital of Soochow University,Jiangsu 215000;Department of Ophthalmology,Kunshan Rehabilitation Hospital;Department of Ultrasound,the Fourth Affiliated Hospital of Soochow University)

机构地区：[1]苏州大学附属第一医院眼科,江苏215000 [2]昆山市康复医院眼科 [3]苏州大学附属第四医院超声科

出　　处：《南通大学学报（医学版）》2024年第4期301-306,共6页Journal of Nantong University(Medical sciences)

基　　金：国家自然科学基金面上项目(81970830);苏州市科技发展计划项目(SKJY2021056)。

摘　　要：目的:评估眼前节生物测量仪Sirius、光学低相干反射仪Lenstar与接触式A超测量白内障患者眼生物参数的差异性和一致性。方法:选取2022年7月—2023年5月于苏州大学附属第一医院就诊的拟行白内障手术的患者121例(121眼)为研究对象,同一观察者分别应用Sirius、Lenstar和接触式A超测量眼生物参数,比较角膜中央厚度(central corneal thickness,CCT)、前房深度(anterior chamber depth,ACD)、眼轴(axial length,AL)、角膜平均K值(average corneal K value,Ave K)、晶状体厚度(lens thickness,LT)和白到白距离(white to white distance,WTW)的结果。对3种仪器的测量结果采用重复测量方差分析及Pearson相关性分析,并以Bland-Altman法进行一致性分析。结果:Lenstar、Sirius测得的CCT值分别为(530.83±29.70)、(538.37±30.49)μm(P<0.001),Bland-Altman分析显示两者一致性较差(95%LoA:-33.6~18.5,差值均值:-7.5);Ave K值分别为(44.05±1.55)、(43.97±1.52)D(P<0.001),Bland-Altman分析显示两者一致性较好(95%LoA:-0.49~0.63,差值均值:0.07);WTW值分别为(11.56±0.37)、(11.31±0.36)mm(P<0.001),Bland-Altman分析显示两者一致性较好(95%LoA:-0.29~0.79,差值均值:0.25);接触性A超、Lenstar、Sirius测得的ACD值分别为(3.03±0.42)、(3.19±0.37)、(3.25±0.37)mm,三者差异有统计学意义(P<0.001),Bland-Altman分析显示两两仪器间的一致性较好(95%LoA分别为:-0.34~0.23,-0.49~0.16,-0.65~0.21,差值均值分别为:-0.05、-0.17、-0.22);接触式A超、Lenstar测量的AL分别为(24.31±2.42)、(24.60±2.51)mm,差异有统计学意义(P<0.001),Bland-Altman分析显示两者的一致性较差(95%LoA:-0.64~0.06,差值均值:-0.29);LT值分别为(4.30±0.60)、(4.32±0.40)mm,差异无统计学意义(P>0.05),Bland-Altman分析显示两者一致性较好(95%LoA:-0.75~0.71,差值均值:-0.02)。Pearson相关性分析显示对于上述眼球参数的测量结果,不同测量方法间均呈正相关。结论:Lenstar和Sirius对于白内障患者眼生物参�Objective:To evaluate the difference and consistency of the biological parameters of ocular biometer Sirius,optical low-coherence reflectivity Lenstar and contact A ultrasound measurement of cataract patients.Methods:121 patients(121 eyes)who had proposed cataract surgery from July 2022 to May 2023 were selected as the study subjects.The same observer used Sirius,Lenstar,and contact A-scan to measure ocular biological parameters,and compared the results of central corneal thickness(CCT),anterior chamber depth(ACD),axial length(AL),average corneal K value(Ave K),lens thickness(LT),and white to white distance(WTW).The results of the three instruments were analyzed by repeated measures ANOVA and Pearson correlation analysis and consistency by Bland-Altman method.Results:The CCT values measured by Lenstar and Sirius were(530.83±29.70)and(538.37±30.49)μm(P<0.001),respectively.The Bland-Altman analysis showed a poor agreement between the two groups(95%LoA:-33.6-18.5,mean difference value:-7.5).The Ave K values were(44.05±1.55),(43.97±1.52)D(P<0.001).The Bland-Altman analysis showed a good agreement between the two groups(95%LoA:-0.49-0.63,mean difference value:0.07).WTW values were(11.56±0.37)and(11.31±0.36)mm(P<0.001).The Bland-Altman analysis showed a good agreement between the two groups(95%LoA:-0.29-0.79,mean difference value:0.25).The ACD values measured for the contact A ultrasound,Lenstar and Sirius are(3.03±0.42),(3.19±0.37),(3.25±0.37)mm,respectively,with statistically significant differences among the three(P<0.001).The Bland-Altman analysis showed good agreement between the two instruments(95%LoA:-0.34-0.23,-0.49-0.16,-0.65-0.21,mean value of the difference is:-0.05,-0.17 and-0.22.The AL measured by contact A-ultrasound and Lenstar are(24.31±2.42)and(24.60±2.51)mm,respectively,with statistically significant difference(P<0.001).The Bland-Altman analysis showed a poor agreement between the two groups(95%LoA:-0.64-0.06,mean difference value:-0.29).The LT values are(4.30±0.60),(4.32±0.40)mm,respect

关 键 词：白内障 生物测量 LENSTAR Sirius A型超声 

分 类 号：R776.1[医药卫生—眼科]