Ⅰ~Ⅱ级肾囊肿去顶术后确诊低度恶性潜能肾肿瘤的诊治经验分析(附8例报告)  

Diagnostic and therapeutic experience in patients diagnosed with renal neoplasm of low malignant potential after Bosniak Ⅰ-Ⅱ renal cyst decortication(Report of 8 cases)

作　　者：王禹琦 潘秀武 陈少军 叶剑青 张良[1] 崔心刚 WANG Yuqi;PAN Xiuwu;CHEN Shaojun;YE Jianqing;ZHANG Liang;CUI Xingang(Department of Urology,Xinhua Hospital Affiliated to Medical College of Shanghai Jiao Tong University,Shanghai,200092,China)

机构地区：[1]上海交通大学医学院附属新华医院泌尿外科,上海200092

出　　处：《临床泌尿外科杂志》2024年第8期730-733,共4页Journal of Clinical Urology

基　　金：新华医院院级临床支撑培育项目(No:21XHDB06)。

摘　　要：目的:探讨术前表现为BosniakⅠ~Ⅱ级肾囊肿,接受肾囊肿去顶降压术后病理确诊为低度恶性潜能多房囊性肾肿瘤患者的影像和病理特征及诊治经验。方法:回顾性分析2018—2023年上海交通大学医学院附属新华医院收治的8例BosniakⅠ~Ⅱ级肾囊肿去顶术后病理确诊低度恶性潜能多房囊性肾肿瘤患者的临床资料,其中男2例,女6例,平均年龄41岁。研究内容包含影像学特征、诊治经过和患者随访情况等。结果:患者术前影像学提示BosniakⅠ~Ⅱ级肾囊肿,术后病理诊断低度恶性潜能多房囊性肾肿瘤。回溯影像典型特征包括囊壁及间隔增厚、强化的高密度灶、内壁毛糙及厚壁样结节等。后续治疗方案包括二期肾部分切除术2例,根治性肾切除术4例,2次治疗窗口期平均2个月(2周~6个月)。患者术后恢复良好,未见复发转移。另2例行积极监测,密切随访未见复发。结论:重视肾脏囊性疾病的术前诊断,提高影像学检查和术中冷冻病理的敏感性,对确诊为低度恶性潜能多房囊性肾肿瘤的患者采取积极治疗,对提升肾脏恶性囊性病变的诊疗具有重要意义。Objective To investigate the imaging and pathological characteristics,as well as diagnostic and treatment experience of patients who pathologically confirmed as multilocular cystic renal neoplasm of low malignant potential after Bosniak Ⅰ-Ⅱ renal cyst decortication.Methods A retrospective analysis was conducted on clinical data of 8 patients diagnosed with multilocular renal cyst neoplasm of low malignant potential after Bosniak Ⅰ-Ⅱ renal cystic decortication at Xinhua Hospital Affiliated to Medical College of Shanghai Jiao Tong University between 2018 and 2023.There were 2 males and 6 females with an average age of 41 years old.The analysis included imaging features,diagnostic and treatment procedures,and patient follow-up outcomes.Results The cases were considered as Bosniak Ⅰ-Ⅱ renal cysts,while pathological results confirmed to be multilocular cystic renal tumor of low malignant potential.A retrospective analysis of imaging revealed typical features which included thickening of cyst walls and septa,enhanced high-density masses,and thick-wall nodules.Follow-up treatments included partial nephrectomy in 2 cases,radical nephrectomy in 4 cases,with an average interval of 2 months(2 weeks to 6 months)between the two procedures.Patients exhibited favorable postoperative recovery and no disease progression was observed.Two patients under active monitoring showed no tumor recurrence.Conclusion The key to improve the diagnosis and curative rate of cystic renal masses is paying attention to preoperative imaging study,intraoperative frozen section examination and active follow-up treatment.

关 键 词：肾囊肿 低度恶性潜能多房囊性肾肿瘤 BOSNIAK分级 囊液分析 

分 类 号：R737.11[医药卫生—肿瘤]