基于EQ-5D-5L的河南省肺癌患者健康相关生命质量状况调查研究  

Health-Related Quality of Life of Lung Cancer Inpatients and the Associated Factors Based on EQ-5D-5L in Henan Province

作　　者：林鑫 耿庆超 冯晨曦 刘茵 张韶凯 LIN Xin;GENG Qingchao;FENG Chenxi;LIU Yin;ZHANG Shaokai(Affiliated Cancer Hospital of Zhengzhou University/Henan Cancer Hospital,Henan Engineering Research Center of Cancer Prevention and Control,Henan International Joint Laboratory of Cancer Prevention,Henan Office for Cancer Control and Prevention,Zhengzhou 450008,China;School of Public Health,Zhengzhou University,Zhengzhou 450001,China)

机构地区：[1]郑州大学附属肿瘤医院/河南省肿瘤医院,河南省肿瘤防控工程研究中心,河南省肿瘤预防国际联合实验室,河南省肿瘤防治办公室,河南郑州450008 [2]郑州大学公共卫生学院,河南郑州450001

出　　处：《中国肿瘤》2024年第9期756-762,共7页China Cancer

基　　金：河南省重点研发专项(221111310200);河南省医学科技攻关计划省部共建重大项目(SBGJ202001004);河南省科技发展计划(232102310166)。

摘　　要：[目的]评估河南省肺癌住院患者的健康相关生命质量(health-related quality of life,HRQOL),并探讨相关影响因素。[方法]基于欧洲五水平五维生命质量量表(EuroQol five-dimensional five-level questionnaire,EQ-5D-5L),采用问卷调查2023年6月至10月间在河南省肿瘤医院住院的肺癌患者的健康相关生命质量状况及健康效用值并分析相关影响因素。[结果]研究共调查299例肺癌住院患者,其健康效用值中位数为0.893,视觉模拟评分刻度尺(visual analogue scale,VAS)评分为(72.26±15.16)分。患者在焦虑/抑郁和疼痛/不舒服两个维度上存在的问题最为突出。Tobit回归分析显示,家庭年支出越高、抚养人数越多和临床分期越晚的患者,其HRQOL越差(P均<0.05)。[结论]肺癌患者的生命质量受家庭经济负担和临床分期影响。未来应当通过医疗保健系统和社会支持体系提供心理支持和经济援助等措施。[Purpose]To survey the health-related quality of life(HRQOL)among lung cancer patients in Henan province and to explore its influencing factors.[Methods]The HRQOL were surveyed with EuroQol five-dimensional five-level questionnaire(EQ-5D-5L)among 300 lung cancer patients admitted in Henan Cancer Hospital from June to October 2022.[Results]A total of 300 questionnaires were distributed and 299 valid ones were returned.The median EQ-5D-5L score was 0.893,and the mean visual analogue scale(VAS)score was 72.26±15.16.Pain/Discomfort and Anxiety/Depression were the most problematic dimensions.The Tobit regression analysis showed that the higher annual household expenditure,the more dependents and later-stage patients were influential factors for reduced HRQOL of lung cancer patients(all P<0.05).[Conclusion]The study shows that the quality of life of lung cancer patients is affected by family financial burden and the pathological stage of the disease.In the future,Measures such as psychological support and financial assistance should be provided through the healthcare system and societal support frameworks.

关 键 词：肺癌 生命质量 欧洲五维生命质量量表 影响因素 

分 类 号：R734[医药卫生—肿瘤]