霉菌毒素对母猪卵子发生产生毒性的作用机制  

Advances of the Toxic Effects of Mycotoxins on Oogenesis of Sows

作　　者：吴冉 李悦彤 庞卫军[1] 蔡瑞 WU Ran;LI Yuetong;PANG Weijun;CAI Rui(College of Animal Science and Technology,Northwest A&F University,Key Laboratory of Animal Genetics,Breeding and Reproduction,Shaanxi Yangling 712100,China)

机构地区：[1]西北农林科技大学动物科技学院,陕西省动物遗传育种与繁殖重点实验室,陕西杨凌712100

出　　处：《中国畜牧杂志》2024年第9期8-14,共7页Chinese Journal of Animal Science

基　　金：国家自然科学基金(32202642);陕西省博士后科研项目(2023BSHEDZZ139);国家生猪产业技术体系(CARS-35-PIG)。

摘　　要：卵子发生是影响母猪繁殖性能高低的重要因素,涉及卵原细胞增殖、卵母细胞生长和成熟3个阶段。环境中存在的黄曲霉毒素、玉米赤霉烯酮、呕吐毒素和伏马毒素等霉菌毒素暴露会引起母猪卵巢、子宫组织病变,干扰卵子发生,对母猪的健康造成不良影响。卵子发生的毒性作用会干扰卵子的正常发育和成熟过程,导致卵子畸形、异常或无法受精,影响母猪的繁殖潜力和生产效益。本文综述了饲料中出现频率较高且危害较大的4种霉菌毒素(黄曲霉毒素、玉米赤霉烯酮、呕吐毒素、伏马毒素)对母猪卵子产生毒性的作用机制,为解决母猪繁殖过程中的激素紊乱、排卵异常和胚胎发育异常等问题提供了重要参考。Oogenesis is an important factor influencing the level of reproductive performance of sows and involves 3 stages:oogonial proliferation,oocyte growth and maturation.Exposure to mycotoxins such as aflatoxin,zearalenone,vomitoxin and fumonisin present in the environment can cause lesions in the ovarian and uterine tissues of sows,interfering with oogenesis and causing adverse effects on sow health.The toxic effects of oogenesis can interfere with the normal development and maturation process of the egg,resulting in malformed,abnormal or unfertilised eggs,affecting the reproductive potential and production efficiency of sows.In this paper,we reviewed the mechanism of action of four mycotoxins(aflatoxin,zearalenone,vomitoxin and fumonisin),which are more frequent and hazardous in feeds,on the toxicity of sows'oocytes,and provided important references to solve the problems of hormonal disorders,ovulatory abnormality,and embryonic development abnormality in sows'reproduction process.

关 键 词：卵子发生 繁殖性状 霉菌毒素 毒性作用 猪 

分 类 号：S828.3[农业科学—畜牧学]