Variation in the Composition of the Essential Oil of Commercial Salvia officinalis L.Leaves Samples from Different Countries  

作　　者：Ain Raal Anne Orav Tetiana Ilina Alla Kovalyova Taras Koliadzhyn Yuliia Avidzba Oleh Koshovyi 

机构地区：[1]Institute of Pharmacy,Faculty of Medicine,University of Tartu,Tartu,50411,Estonia [2]Institute of Chemistry,Tallinn University of Technology,Tallinn,12618,Estonia [3]The Department of Pharmaceutical Management,Drug Technology and Pharmacognosy,Ivano-Frankivsk National Medical University,Ivano-Frankivsk,76018,Ukraine [4]The Department of Pharmacognosy,National University of Pharmacy,Kharkiv,61002,Ukraine [5]The Department of Clinical Laboratory Diagnostics,Kharkiv National Medical University,Kharkiv,61022,Ukraine

出　　处：《Phyton-International Journal of Experimental Botany》2024年第8期2051-2062,共12页国际实验植物学杂志（英文）

基　　金：the MSCA4 Ukraine project“Design and Development of 3D-Printed Medicines for Bioactive Materials of Ukrainian and Estonian Medicinal Plants Origin”(ID Number 1232466)and financed by the European Union.

摘　　要：Salvia officinalis L.(Lamiaceae)leaves and its essential oil is used for mouth and throat disorders,skin disorders,minor wounds,and gastrointestinal disorders,and is widely used worldwide.The research aimed to conduct a comparative study of the composition of S.officinalis essential oils from commercial samples,and their main chemotypes.The volatile constituents from S.officinalis leaves were investigated using gas chromatography(GC).The commercial samples of sage leaves were obtained from retail pharmacies in nine mainly European countries.The yield of essential oil in S.officinalis commercial leaves was between 10.0 and 24.8 mL/kg.The principal components(>5%)among the main identified 25 compounds were 1,8-cineole(8.3%–45.3%),α-thujone(3.0%–34.0%),сamphor(11.3%–29.3%),β-thujone(1.5%–12.9%),viridiflorol(1.1%–10.4%),camphene(2.6%–7.1%),andα-pinene(1.3%–5.8%).In seven(Estonia,England,France,Hungary,Belgium,Ukraine,Georgia)samplesα-thujone dominated.Four samples(Estonia,Georgia,England,Hungary)belong to the most common chemotypeα-thujone>camphor>1,8-cineole.Eight chemotypes of S.officinalis essential oils have been found.Toxic thujones are widespread compounds among them.

关 键 词：SAGE TERPENOIDS CHEMOTYPES thujone TOXICITY 

分 类 号：Q94[生物学—植物学]