5A模式干预对肺癌靶向治疗患者负性情绪、自我感受负担及生活质量的影响  

Effect of 5A model intervention on negative emotions,self-perceived burden and A quality of life in patients with lung cancer undergoing targeted therapy

作　　者：孙丹 杨英[1] 徐璐[1] SUN Dan;YANG Ying;XU Lu(Department of Respiratory Medicine,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,He’nan,China)

机构地区：[1]郑州大学第一附属医院呼吸内科,郑州450000

出　　处：《癌症进展》2024年第16期1852-1856,共5页Oncology Progress

摘　　要：目的探讨5A模式干预对肺癌靶向治疗患者负性情绪、自我感受负担及生活质量的影响。方法根据干预方法的不同将105例肺癌靶向治疗患者分为对照组(n=50,常规干预)和观察组(n=55,5A模式干预)。比较两组患者的负性情绪[汉密尔顿焦虑量表(HAMA)、汉密尔顿抑郁量表(HAMD)]、自我感受负担[自我感受负担量表(SPBS)]、生活质量[欧洲癌症研究与治疗组织生命质量测定量表(EORTC QLQ-C30)]、不良反应发生情况、依从性及满意度。结果干预后,两组患者HAMA、HAMD、SPBS评分均低于本组干预前,观察组患者HAMA、HAMD、SPBS评分均低于对照组,差异均有统计学意义(P﹤0.05)。干预后,两组患者EORTC QLQ-C30各维度评分均高于本组干预前,观察组患者EORTC QLQ-C30各维度评分均高于对照组,差异均有统计学意义(P﹤0.05)。观察组患者骨髓抑制、呕吐、头晕、感染发生率均低于对照组,差异均有统计学意义(P﹤0.05)。观察组患者的总依从率和满意度评分均高于对照组,差异均有统计学意义(P﹤0.05)。结论5A模式干预可改善肺癌靶向治疗患者的负性情绪,减轻自我感受负担,提高生活质量、依从性及满意度,降低并发症发生率。Objective To explore the effect of 5A model intervention on negative emotions,self-perceived burden and quality of life in patients with lung cancer undergoing targeted therapy.Method According to different intervention methods,105 patients with lung cancer who received targeted therapy were divided into control group(n=50,convention-al intervention)and observation group(n=55,5A model intervention).The negative emotions[Hamilton anxiety scale(HAMA),Hamilton depression scale(HAMD)],self-perceived burden[self-perceived burden scale(SPBS)],quality of life[European Organization for Research and Treatment of Cancer quality of life questionnaire core 30(EORTC QLQ C30)],occurrence of adverse reactions,compliance and satisfaction were compared between the two groups.Result Af-ter intervention,the HAMA,HAMD and SPBS scores in both groups were lower than those before intervention,and the HAMA,HAMD and SPBS scores in observation group were lower than those in control group,and the differences were statistically significant(P<0.05).After intervention,the scores of each dimension of EORTC QLQ-C30 in both groups were higher than those before intervention,and the scores of each dimension of EORTC QLQ-C30 in observation group were higher than those in control group,and the differences were statistically significant(P<0.05).The incidence rates of myelosuppression,vomiting,dizziness and infection in observation group were lower than those in control group,and the differences were statistically significant(P<0.05).The total compliance rate and satisfaction score of the observation group were higher than those of the control group,and the differences were statistically significant(P<0.05).Conclusion 5A model intervention can improve the negative emotions of patients with lung cancer undergoing targeted therapy,re-duce the self-perceived burden,improve the quality of life,compliance and satisfaction,and reduce the incidence of com-plications.

关 键 词：5A模式干预 靶向治疗 肺癌 负性情绪 自我感受负担 生活质量 

分 类 号：R734.2[医药卫生—肿瘤]