从肝脾论治视网膜静脉阻塞继发黄斑水肿  

Treatment of Macular Edema Secondary to Retinal Vein Occlusion from the Perspective of Liver and Spleen

作　　者：张孟姣 郝晓凤[1] 谢立科[1] 赵宇晗 罗傑 孙梅 王丹 ZHANG Meng-jiao;HAO Xiao-feng;XIE li-ke;ZHAO Yu-han;LUO Jie;SUN Mei;WANG Dan(Surgical Department of Ocular Fundus Disease,Eye Hospital of China Academy of Chinese Medical Sciences,Beijing 100040;China Academy of Chinese Medical Sciences,Bejing 100700)

机构地区：[1]中国中医科学院眼科医院眼底病眼外科,北京100040 [2]中国中医科学院,北京100700

出　　处：《世界中西医结合杂志》2024年第9期1872-1875,共4页World Journal of Integrated Traditional and Western Medicine

基　　金：国家自然科学基金青年基金(81603666);首都临床特色应用研究重点研发项目(Z181100001718183);“优势病种-医院制剂-新药”研发专项(ZZ15-XY-PT-09);北京市自然科学基金资助项目(7192235)。

摘　　要：根据肝脾与目的关系,从肝脾两脏生理上相互为用、病理上相互传变的特点出发,分析肝郁脾虚在视网膜静脉阻塞继发黄斑水肿(Macular edema secondary to retinal vein occlusion,RVO-ME)发生发展中的作用,结合疾病临床特点,认为RVO-ME的病机本质为肝郁脾虚,以致痰湿等病理产物堆积,形成肝郁脾虚-痰湿瘀血-肝郁脾虚的恶性循环,致使机体正虚邪实形成黄斑水肿。因此文中从肝脾理论出发,以疏肝健脾为主要治疗原则,以期丰富RVO-ME的中医病机理论和临床辨证施治证据。Based on the physiological relationship between the liver and spleen and their mutual influence pathologically,this article analyzed the role of liver stagnation and spleen deficiency in the occurrence and development of macular edema secondary to retinal vein occlusion(RVO-ME).Combining the clinical characteristics of the disease,it is proposed that the essential pathogenesis of RVO-ME is rooted in liver stagnation and spleen deficiency,leading to the accumulation of pathological products such as phlegm and dampness.This results in a vicious cycle of liver stagnation and spleen deficiency-phlegm-dampness and blood stasis-further exacerbating liver stagnation and spleen deficiency.This pathological cycle weakens the body′s healthy qi,allowing pathogenic factors to dominate and causing macular edema.Therefore,based on the theory of liver and spleen,the main treatment principle is to soothe the liver and strengthen the spleen,aiming to enrich the theoretical understanding of the pathogenesis of RVO-ME in traditional Chinese medicine and provide clinical evidence for syndrome differentiation and treatment.

关 键 词：视网膜静脉阻塞继发黄斑水肿 肝脾理论 肝郁脾虚 疏肝健脾 

分 类 号：R774[医药卫生—眼科]