Dynamic steric confinement effect expands the frontier of Cu-catalyzed asymmetric propargylic aminations  

作　　者：Peng Chen Mao-Mao Zhang Wen-Jing Xiao Liang-Qiu Lu 

机构地区：[1]Engineering Research Center of Photoenergy Utilization for Pollution Control and Carbon Reduction,Ministry of Education,College of Chemistry,Central China Normal University,Wuhan 430079,China [2]Wuhan Institute of Photochemistry and Technology,Wuhan 430082,China [3]State Key Laboratory for Oxo Synthesis and Selective Oxidation,Lanzhou Institute of Chemical Physics(LICP),Chinese Academy of Sciences,Lanzhou 730000,China [4]School of Chemistry and Chemical Engineering,Henan Normal University,Xinxiang 453007,China

出　　处：《Science China Chemistry》2024年第10期3181-3183,共3页中国科学（化学英文版）

摘　　要：Chiralα-tertiary amines and related azacycles are commonly found in many natural products,pharmaceuticals and agrochemicals[1].Copper-catalyzed asymmetric propargylic amination(APA)reactions have been established as a reliable method to access enantio-enriched propargylic amines,largely due to the seminal contribution of Nishibayashi et al.[2]and van Maarseveen et al.[3]in 2008.

关 键 词：CATALYZED ASYMMETRIC AMINES 

分 类 号：O621.251[理学—有机化学]