基于ClinicalTrials.gov探讨慢性胰腺炎治疗研究新进展  

Progress in treatment of chronic pancreatitis:A review based on the ClinicalTrials.gov database

作　　者：姜凌莹 韩超 胡良皞 Ling-Ying Jiang;Chao Han;Liang-Hao Hu(School of Basic Medicine,Naval Medical University,Shanghai 200433,China;Hospital of 91876 Troops of Chinese People’s Liberation Army,Qinhuangdao 066203,Hebei Province,China;Department of Gastroenterology,Naval Medical Center,Naval Medical University,Shanghai 200052,China;Department of Gastroenterology,First Affiliated Hospital of Naval Medical University,Shanghai 200433,China)

机构地区：[1]海军军医大学基础医学院,上海市200433 [2]中国人民解放军91876部队医院,河北省秦皇岛市066203 [3]海军军医大学海军特色医学中心消化内科,上海市200052 [4]海军军医大学第一附属医院消化内科,上海市200433

出　　处：《世界华人消化杂志》2024年第9期635-644,共10页World Chinese Journal of Digestology

基　　金：国家自然科学基金,No.82270679和No.82070664.

摘　　要：慢性胰腺炎(chronic pancreatitis,CP)是指各种病因引起的胰腺慢性进行性炎症性纤维化疾病,临床表现为反复发作的上腹部疼痛和胰腺外分泌功能不全.ClinicalTrials.gov是目前国际上应用最广泛的临床试验数据库,主要包含已完成的、正在开展的和即将进行的临床研究的信息.本文通过对ClinicalTrials.gov数据库中所有于2024-06-30前注册的临床研究进行检索,筛选出最新的CP相关的临床研究,从营养支持、药物、内镜等角度整理归纳CP临床研究的方向和热点,旨在为今后CP临床研究的设计拓展新思路.Chronic pancreatitis(CP)is a chronic progressive fibro-inflammatory disease of the pancreas caused by various etiologies,characterized by recurrent upper abdominal pain and pancreatic exocrine dysfunction.ClinicalTrials.gov is the most commonly used clinical trial database,including information of clinical trials which have been completed or are ongoing,or upcoming.Based on the ClinicalTrials.gov database,we retrieved all clinical studies registered before June 30,2024,screened out recent clinical studies related to CP,and summarized and integrated highlights and directions of these studies from the perspectives of nutritional support,medication,endoscopy,etc.,aiming to provide new ideas for the design of CP clinical studies in the future.

关 键 词：慢性胰腺炎 消化内镜 疼痛 临床试验 ClinicalTrials.gov 

分 类 号：R576[医药卫生—消化系统]