两种透析方法下单中心老年慢性肾脏病患者的营养状况比较分析  

COMPARATIVE ANALYSIS OF THE NUTRITIONAL STATUS OF ELDERLY CHRONIC KIDNEY DISEASE PATIENTS IN A SINGLE CENTER UNDER TWO DIALYSIS METHODS

作　　者：吴昊天 叶晨露 张凯 姜美琦 孟彦 吴静[5] WU Haotian;YE Chenlu;ZHANG Kai;JIANG Meiqi;MENG Yan;WU Jing(School of Public Health,Inner Mongolia Medical University,Inner Mongolia,010110,China;College of Medical Humanities and Management,Wenzhou Medical University,Wenzhou,Zhejiang 325035,China;Department of Epidemiology,School of Public Health,China Medical University,Shenyang,Liaoning,110000,China;Affiliated Hospital of Inner Mongolia Medical University,Hohhot,Inner Mongolia,010110,China;National Center for Chronic and Noncommunicable Disease Control and Prevention,Beijing,100050,China)

机构地区：[1]内蒙古医科大学公共卫生学院,内蒙古呼和浩特010110 [2]温州医科大学医学人文与管理学院,浙江温州325035 [3]中国医科大学公共卫生学院流行病学教研室,辽宁沈阳110000 [4]内蒙古医科大学附属医院肾内科,内蒙古呼和浩特010110 [5]中国疾病预防控制中心慢性非传染性疾病预防控制中心,北京100050

出　　处：《内蒙古医科大学学报》2024年第3期328-332,共5页Journal of Inner Mongolia Medical University

基　　金：研究生科技创新卓越人才培养计划项目(YKD2023ZY020)。

摘　　要：目的研究老年慢性肾脏病(chronic kidney disease,CKD)患者接受血液透析和腹膜透析后的营养状况,并分析不同透析方式对其营养水平的影响,以便为改进营养不良的干预措施提供依据。方法利用问卷调查和内蒙古医科大学附属医院的科研数据平台,对2023年1月至3月接受透析的144名老年CKD患者进行营养状况评估,此外收集了人口学和实验室数据,分析了不同透析方式对营养素缺失的影响。结果在调查的144名患者中,111人存在营养不良风险,与年龄(P<0.05)和透析方式(P<0.05)有显著关联。此外,不同透析方式对血红蛋白、磷和总胆固醇的影响差异存在统计学意义(P<0.05)。血液透析在血红蛋白和磷的影响较大,而腹膜透析在总胆固醇上的影响更明显。结论老年CKD患者的营养不良与年龄和透析方式密切相关,要改善患者营养状态,需针对上述因素实施有效干预。Objective The aim of this study is to examine the nutritional status of elderly patients with chronic kidney disease(CKD)who are undergoing hemodialysis and peritoneal dialysis.Additionally,the study seeks to evaluate the impact of various dialysis modalities on the nutritional status of these patients,with the goal of enhancing interventions for malnutrition.Methods Utilizing questionnaires and the research data platform of Inner Mongolia Medical University Hospital,a study was conducted to evaluate the nutritional status of 144 elderly CKD patients undergoing dialysis between January and March 2023.Additionally,demographic and laboratory data were gathered to investigate the impact of various dialysis modalities on nutrient deficiencies.Results Among the 144 patients examined,111 were identified as being at risk of malnutrition,showing notable correlations with age(P<0.001)and dialysis method(P=0.021).Significant variations were observed in the impact of various dialysis modalities on hemoglobin(P<0.001),phosphorus(P=0.015),and total cholesterol(P=0.005).Hemodialysis exerted a more pronounced impact on hemoglobin and phosphorus levels,whereas peritoneal dialysis demonstrated a greater influence on total cholesterol levels.Conclusions The occurrence of malnutrition in elderly chronic kidney disease(CKD)patients is significantly associated with age and the type of dialysis utilized.In order to enhance the nutritional well-being of these patients,it is imperative to introduce effective interventions that specifically target these factors.

关 键 词：老年慢性肾脏病 透析方法 营养状况 

分 类 号：R737.33[医药卫生—肿瘤]