2006—2023年厦门市美沙酮维持治疗门诊患者状况分析  

Patient Status of Methadone Maintenance Treatment Clinics from 2006 to 2023 in Xiamen

作　　者：马桂林[1] 张婉君 柯然[1] 邓晖文 MA Guilin;ZHANG Wanjun;KE Ran;DENG Huiwen(Xiamen Center for Disease Control and Prevention,Xiamen 361021,Fujian,China)

机构地区：[1]厦门市疾病预防控制中心结艾处,福建厦门361021

出　　处：《中国药物滥用防治杂志》2024年第9期1581-1585,共5页Chinese Journal of Drug Abuse Prevention and Treatment

基　　金：福建省卫生健康科技计划项目资助(编号:2022GGB014)。

摘　　要：目的:分析2006—2023年厦门市美沙酮维持治疗(methadone maintenance treatment,MMT)门诊患者状况,为后续更好地开展MMT工作提供参考。方法:数据来源于国家戒毒药物维持治疗数据信息系统。对2006—2023年厦门市MMT门诊患者一般特征、治疗人数、日均服药量、尿吗啡检测阳性率及艾滋病病毒(HIV)、丙肝病毒(HCV)感染情况等指标进行分析。结果:厦门市MMT门诊患者以男性(84.68%)、汉族(84.77%)为主,年龄集中在30~49岁。2006—2023年期间在治人数从323人上升至1438人后逐年下降。较少患者能坚持长期维持治疗,坚持治疗10年及以上的仅134人,坚持治疗满17年的只有3人。日均服药量从37.7 mg上升至59.93 mg后开始下降。尿吗啡检测阳性率则从63.32%持续下降至0.33%。累计有26例HIV感染者接受了MMT。累计丙型肝炎病毒(HCV)阳性率达70.02%。结论:厦门市MMT工作已取得一定成效,但面临着治疗人数下降、HCV阳性率较高等问题,需采取针对性的解决措施。Objective:To analyze the patient status of methadone maintenance treatment(MMT)clinics in Xiamen,in order to provide reference for improvement measures.Methods:Data were collected from the information system of Chinese maintenance treatment program.The related data such as general characteristics,the number of patients,average daily dose was analyzed.Results:Most patients were male and between 30-49 years old.The number of patients increased from 323 to 1438 first and then declined during 2006 and 2023.Few patients could persist in long-term maintenance treatment.The average daily dose increased from 37.7 mg to 59.93 mg first and then declined.The positive rate of urine morphine continued to decrease from 63.32%to 0.33%.Total of 26 patients infected HIV received MMT.The cumulative positive rate of hepatitis C virus(HCV)reached 70.02%.Conclusion:The MMT work in Xiamen has achieved phased result.Corresponding measures should be carried out to address issues such as declining treatment numbers and high positive rate of HCV.

关 键 词：美沙酮维持治疗 艾滋病病毒 治疗人数 状况 

分 类 号：R749.64[医药卫生—神经病学与精神病学]