非肌层浸润性膀胱癌TURBT术后尿路感染与膀胱痉挛的关系及影响因素分析  

Relationship between urinary tract infection and bladder spasm after TURBT in early non muscle invasive bladder cancer

作　　者：王安勇[1] Wang Anyong(Department of Urology,Ya′an People′s Hospital,Ya′an 625000,China)

机构地区：[1]四川省雅安市人民医院泌尿外科,雅安625000

出　　处：《国际泌尿系统杂志》2024年第5期846-850,共5页International Journal of Urology and Nephrology

基　　金：四川省卫健委课题(17PJ034)。

摘　　要：目的探讨早期非肌层浸润性膀胱癌经尿道膀胱肿瘤电切术(TURBT)后尿路感染、膀胱痉挛的发生情况及其影响因素。方法选取2014年1月至2021年5月在本院治疗的244例早期非肌层浸润性膀胱癌患者的临床资料,观察患者的术后尿路感染、膀胱痉挛发生情况,比较分析发生和未发生尿路感染、发生和未发生膀胱痉挛患者的临床资料。结果患者的术后尿路感染发生率为18.03%(44/244),术后膀胱痉挛发生率为31.15%(76/244)。术后发生尿路感染患者的年龄≥60岁、多发肿瘤、糖尿病、有导尿管堵塞、术后留置导尿管时间>7 d、术后发生膀胱痉挛的比例均明显高于未发生尿路感染患者(均P<0.05)。多因素logistic回归分析结果显示:年龄、糖尿病、导尿管堵塞和术后留置导尿管时间是术后尿路感染的影响因素(均P<0.05)。术后发生膀胱痉挛患者的年龄≥60岁、糖尿病、手术时间>1 h、导尿管堵塞、术后留置导尿管时间>7 d的比例均明显高于未发生膀胱痉挛患者(均P<0.05)。多因素logistic回归分析结果显示:年龄、手术时间和导尿管堵塞是术后膀胱痉挛发生的影响因素(均P<0.05)。结论早期非肌层浸润性膀胱癌行TURBT术后尿路感染和膀胱痉挛的发生率较高,尿路感染发生受患者年龄、导尿管堵塞等因素影响;膀胱痉挛发生受患者年龄、手术时间等因素影响,但与术后尿路感染无明显关联。ObjectiveTo investigate the incidence and influencing factors of urinary tract infection and bladder spasm after transurethral resection of bladder tumor(TURBT)for early non muscle invasive bladder cancer.MethodsThe clinical data of 244 patients with early-stage non-muscular invasive bladder cancer treated in our hospital from January 2014 to May 2021 were selected to observe the occurrence of postoperative urinary tract infection and bladder spasm,and to compare and analyze the clinical data of patients with and without urinary tract infection and bladder spasm.ResultsThe incidence of postoperative urinary tract infection was 18.03%(44/244)and the incidence of postoperative bladder spasm was 31.15%(76/244).The proportion of patients with postoperative urinary tract infection with age≥60 years,multiple tumors,diabetes,catheter blockage,catheter retention time>7 days and postoperative bladder spasm was significantly higher than that of patients without urinary tract infection(all P<0.05).Multivariate logistic regression analysis showed that age,diabetes,catheter blockage and catheter indwelling time were the influencing factors of postoperative urinary tract infection(all P<0.05).The proportion of patients with postoperative bladder spasm who were≥60 years,diabetes mellitus,operation time>1 h,catheter blockage and postoperative catheter retention time>7 days were significantly higher than those without bladder spasm(all P<0.05).Multivariate logistic regression analysis showed that age,operation time and catheter blockage were the influencing factors of postoperative bladder spasm(all P<0.05).ConclusionsThe incidence of urinary tract infection and bladder spasm after TURBT in early non muscle invasive bladder cancer is high,the occurrence of urinary tract infection is affected by the patient′s age,urinary catheter blockage and other factors,the occurrence of bladder spasm is affected by the patient′s age,operation time and other factors,but is not related with postoperative urinary tract infection.

关 键 词：膀胱肿瘤 膀胱切除术 尿路感染 膀胱痉挛 

分 类 号：R737.14[医药卫生—肿瘤]