Photochemical reactions as synthetic tool for pharmaceutical industries  

作　　者：Shehla Khalid Muhammad Bilal Nasir Rasool Muhammad Imran 

机构地区：[1]Department of Chemistry,Government College University,Faisalabad 38000,Pakistan [2]School of Chemistry and Chemical Engineering,Shandong University,Ji’nan 250100,China [3]Department of Chemistry,Faculty of Science,King Khalid University,Abha 61413,Saudi Arabia

出　　处：《Chinese Chemical Letters》2024年第9期9-31,共23页中国化学快报（英文版）

摘　　要：In the quest for new agrochemicals and pharmaceuticals,chemists seek access to reliable and mild synthetic techniques to allow for the systematic modification of chemical structures,exploration of unexplored chemical space,and facilitation of practical synthesis in their search for novel agrochemicals and pharmaceuticals.In this regard,photocatalytic reactions enabled the synthesis of intricate and more functionalized compounds.This review overviews the developed synthetic methodologies and their utility in the chemical synthesis of pharmaceuticals.This review also offers in-depth insights into contemporary photoredox reactions such as allylic additions,cyclization,reductive cross-coupling,C–H activation,ring opening,oxidative cross-coupling,dehydrogenation,desulphonation,and decarboxylation.It provides a positive outlook for the promising future of this field.

关 键 词：PHOTOCATALYST Photochemical reactions DRUGS Natural products Late-stage functionalization 

分 类 号：TQ460.3[化学工程—制药化工] O644.1[理学—物理化学]