高帧频超声造影与CT在评估乳腺癌前哨淋巴结状态中的应用价值  

The Application Value of High-Frame-Frequency Contrast-Enhanced Ultrasound versus CT in Assessing the Status of Sentinel Lymph Nodes in Breast Cancer

作　　者：高文祥 尹明 GAO Wen-xiang;YIN Ming(The Affiliated Taizhou People's Hospital of Nanjing Medical University,Taizhou Jiangsu 225300,China)

机构地区：[1]南京医科大学附属泰州人民医院,江苏泰州225300

出　　处：《泰州职业技术学院学报》2024年第5期71-74,共4页Journal of Taizhou Polytechnic College

摘　　要：目的探讨高帧频超声造影(H-CEUS)及电子计算机断层扫描(CT)在评估乳腺癌腋窝前哨淋巴结(SLN)状态中的应用。方法随机选取2020年3月~2023年5月于本院行单侧乳腺癌接受手术治疗的54例患者。所有研究对象术前均采用H-CEUS与CT行单侧SLN扫查,共检出72肿大淋巴结,同时记录各自描述SLN的声学图像特点。根据手术治疗后术后SLN组织病理结果,将所有研究对象分为淋巴结非转移组(n=22例)与转移组(n=50例)。进一步分析H-CEUS、CT以及以上两种手段联合检测的灵敏度、特异度、阳性预测值、阴性预测值。结果H-CEUS共检出转移性淋巴结49例和非转移性淋巴结23例,而CT共检出转移性淋巴结47例和非转移性淋巴结25例。与术后病理结果对比分析发现,H-CEUS的灵敏度、特异度、准确度分别为86.00%、72.73%以及81.94%;CT的灵敏度、特异度、准确度分别为78.00%、63.64%与73.61%。H-CEUS联合CT检查的灵敏度、特异度、准确度分别为92.00%、86.36%以及90.28%,均高于单一H-CEUS、CT检查的诊断效能(P<0.05)。结论H-CEUS、CT能够评估乳腺癌SLN是否存在早期转移性病变,其中高超声造影对乳腺癌的SLN早期转移预测价值较大(P<0.05),两者联合预测价值最大(P<0.05)。Objective To explore the application of H-CEUS and CT in assessing the status of SLN in breast cancer.Methods Fifty-four patients who underwent surgical treatment for unilateral breast cancer from March 2020 to May 2023 at our hospital were randomly selected.All study subjects underwent preoperative unilateral SLN scanning using H-CEUS with CT,and a total of 72 enlarged lymph nodes were detected,while the respective acoustic image characteristics describing the SLN were recorded.Based on the histopathological findings of postoperative SLN after surgical treatment,all study subjects were divided into lymph node non-metastatic group(n=22 cases)and metastatic group(n=50 cases).The sensitivity,specificity,positive predictive value,and negative predictive value of H-CEUS,CT,and the combined detection of the above two means were further analyzed.Results H-CEUS detected a total of metastatic lymph node cases and non-metastatic lymph node cases,while CT detected a total of metastatic lymph node cases and non-metastatic lymph node cases.Comparison with postoperative pathological results showed that the sensitivity,specificity and accuracy of H-CEUS were 86.00%,72.73%and 81.94%,respectively,while those of CT were 78.00%,63.64%and 73.61%,respectively.The sensitivity,specificity,and accuracy of H-CEUS combined with CT were 92.00%,86.36%,and 90.28%,respectively,which were higher than those of single H-CEUS and CT(P<0.05).Conclusion H-CEUS and CT were able to assess the presence of early metastatic lesions in SLN of breast cancer,in which high-frequency ultrasonography had a greater predictive value of early metastasis in SLN of breast cancer(P<0.05),and the combination of the two had the greatest predictive value(P<0.05).

关 键 词：乳腺癌 前哨淋巴结 高帧频超声造影 CT 

分 类 号：R737.9[医药卫生—肿瘤] R445.1[医药卫生—临床医学]