Imaging mass spectrometry:a molecular microscope for studying the role of lipids in Parkinson's disease  

作　　者：Vinata Vedam-Mai Jacob M.Samuel Boone M.Prentice 

机构地区：[1]Department of Neurology,University of Florida,Gainesville,FL,USA [2]Department of Chemistry,University of Florida,Gainesville,FL,USA

出　　处：《Neural Regeneration Research》2024年第6期1179-1180,共2页中国神经再生研究（英文版）

摘　　要：Parkinson's disease–A lipidopathy?The histopathological hallmark of Parkinson's disease(PD)and dementia with Lewy bodies are inclusions enriched inα-synuclein(α-syn),known as Lewy bodies,which are not only composed of proteins,but also a core of lipid species.PD has been thus far principally thought of as a“proteinopathy”caused by the misfolding of α-syn.

关 键 词：LIPIDS SPECIES FOLDING 

分 类 号：R742.5[医药卫生—神经病学与精神病学]