肠道菌群在炎症性肠病相关肠纤维化中的作用研究进展  

Advances in the role of intestinal flora in intestinal fibrosis associated with inflammatory bowel disease

作　　者：王硕 苏文豪 刘传 董卫国[1] WANG Shuo;SU Wenhao;LIU Chuan;DONG Weiguo(Department of Gastroenterology,Renmin Hospital of Wuhan University,Wuhan 430060,China)

机构地区：[1]武汉大学人民医院消化内科,湖北武汉430060

出　　处：《胃肠病学和肝病学杂志》2024年第10期1368-1371,共4页Chinese Journal of Gastroenterology and Hepatology

基　　金：国家自然科学基金项目(82170549)。

摘　　要：炎症性肠病包括溃疡性结肠炎和克罗恩病,肠纤维化是其常见的晚期并发症之一,目前仍无较好的非手术治疗手段。肠道菌群与IBD的发生发展密切相关,且已在多种器官纤维化中证实其作用。本文将就已有的肠道菌群在IBD相关肠纤维化中的研究进展作一综述,以期为明确IBD患者中肠道菌群和肠纤维化的相互作用提供参考依据。Inflammatory bowel disease includes ulcerative colitis and Crohn′s disease,for which intestinal fibrosis is one of the common late complications and for which there is still no better non-surgical treatment.Intestinal flora is closely associated with the development of IBD and its role has been demonstrated in a variety of organ fibrosis.In this paper,we reviewed the available research progress on intestinal flora in IBD-related intestinal fibrosis to provide a reference for clarifying the interaction between intestinal flora and intestinal fibrosis in IBD patients.

关 键 词：肠道纤维化 肠道菌群 益生菌 炎症性肠病 

分 类 号：R574.6[医药卫生—消化系统]