Well water contaminants and colorectal cancer in North Dakota  

作　　者：Amber D Lyon-Colbert Marc D Basson Marilyn G Klug Gary G Schwartz 

机构地区：[1]Department of Population Health,University of North Dakota,Grand Forks,ND 58202,United States [2]College of Medicine,Northeast Ohio Medical University,Rootstown,OH 44272,United States [3]College of Medicine,University Hospitals,Cleveland,OH 44106,United States [4]Department of Population Health,University of North Dakota School of Medicine and Health Sciences,Grand Forks,ND 58202,United States

出　　处：《World Journal of Clinical Oncology》2024年第11期1454-1458,共5页世界临床肿瘤学杂志（英文）

基　　金：Supported by The National Institute of General Medical Sciences(NIGMS),No.1P20GM155890-01 to GGS.

摘　　要：This study aims to identify common contaminants in well water linked to an increase in colorectal cancer(CRC)incidence rates in North Dakota(ND)counties.County-specific incidence rates for CRC were obtained from the ND Statewide Cancer Registry.Corresponding demographic,agricultural,and geophysical data were obtained from population-based sources.Associations between well water contaminants and CRC incidence were examined for 16 counties in ND with complete well water profiles between 1997-2019.Data were analyzed by multiple linear regression.Iron in well water exhibited a significant positive association with CRC incidence(4.75,P=0.001),and barium exhibited a small,but significant negative association(-0.06907,P=0.01).Residents in counties in ND with prevalent well water usage contaminated with iron may be at higher risk for CRC.

关 键 词：Colorectal cancer IRON Water quality Well water North Dakota 

分 类 号：R735.34[医药卫生—肿瘤]