Tricuspid mass-curious case of Li-Fraumeni syndrome:A letter to the editor  

作　　者：Mohammad S Al-Haggar Zahraa A Abdelmoneim 

机构地区：[1]Department of Pediatrics and Genetics,Mansoura University Children's Hospital,Mansoura 35516,Egypt [2]Department of Pediatrics,Genetic Unit,Mansoura University Children Hospital,Mansoura 35516,Egypt

出　　处：《World Journal of Clinical Cases》2024年第33期6644-6646,共3页世界临床病例杂志（英文）

摘　　要：We focus specifically on the rare occurrence of cardiac thrombi in Li-Fraumeni syndrome(LFS).LFS is a hereditary risk to a diverse range of specific,uncommon,malignancies.Children and young adults have a heightened susceptibility to many malignancies,particularly soft-tissue and bone tumors,breast malignancies,central nervous system malignancies,adrenocortical carcinoma,and blood cancers.Additionally,LFS patients may experience other cancer types such as gastrointestinal,lung,kidney,thyroid,and skin cancers,along with those affecting gonadal organs(ovaries,testicles,and prostate).An accurate diagnosis of LFS is crucial to enable affected families to access appropriate genetic counseling and undergo surveillance for early cancer detection.

关 键 词：Li-Fraumeni syndrome CANCERS Cardiac thrombus Genetic counseling SURVEILLANCE 

分 类 号：R54[医药卫生—心血管疾病]