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CANCERS: 作品数：353被引量：2621H指数：17; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：夏厚军陈策实徐留柱刘端祺介雅慧更多>>; 相关机构：中南大学南京医科大学教育部中国科学院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金福建省自然科学基金更多>>

Oncogenic activation of PIK3CA in cancers:Emerging targeted therapies in precision oncology: 《Genes & Diseases》2025年第2期143-153,共11页Yuxiang Wang Valery Rozen Yiqing Zhao Zhenghe Wang; supported by the National Institutes of Health (USA)grantsSR01CA196643,R01CA264320,R01CA260629,P50CA150964,and P30CA043703 to Zhenghe Wang.; Phosphoinositide 3-kinases(PI3Ks)are heterodimers consisting of a p110 catalytic subunit and a p85 regulatory subunit.The PlIK3CA gene,which encodes the p110a,is the most frequently mutated oncogene in cancer.Oncogeni...; 关键词：Hotspot mutation Isoform/mutant-specific inhibitors Metabolism PIK3CA Tumor microenvironment

Physiological Variance of CD34 Marker’s Content in Twenty Tissues Determining Different Risks of Cardiovascular Diseases and Cancer in Them: 《Open Journal of Biophysics》2025年第1期1-17,共17页Aleksey N. Shoutko Marat A. Karamullin; The decreasing of hazard ratio for cancer incidence (HRCVD) in the range of twenty native tissues (lung, liver, brain, hematologic, neuroendocrine renal, pancreas, lymphoid, bladder, colon, lip-oral-head-neck, leukocy...; 关键词：Population Cardiovascular Pathology CANCERS Interrelation TISSUES CD Markers Prognostic Value Revision

Study of Non-Genetic Risk Factors for Breast Cancer in Young Women at the Gynecology-Obstetrics Clinic of CHU Sylvanus Olympio in Lomé, Togo: 《Open Journal of Obstetrics and Gynecology》2025年第2期224-234,共11页Ameyo Ayoko Ketevi Kokouvi Adjewoda Kougnaglo Kossi Edem Logbo-Akey Komla Alexi Andele Abdoul Samadou Aboubakari Akila Bassowa Baguilane Douaguibe Dede Regine Diane Ajavon Tchin Darre Koffi Akpadza; Introduction: Considering a disease of postmenopausal women, there is a noted trend of increasing breast cancer cases among premenopausal women. Our study aimed to determine the main risk factors for breast cancer in ...; 关键词：CANCERS Breast Risk Factors Young Women

Encrypting Cancer’s Morse Code: The Synergistic Power of CD47-SIRPα Blockade and Tyrosine Kinase Inhibition: 《International Journal of Clinical Medicine》2025年第2期135-153,共19页Mahamud Hirsi Yahya Lahrach Abdirahman Mohamud Abdirahman Amina Nazir Mohamed Abshir Barre Yasmine Yusuf Hussein Dinle Abdulrahman Wajih Alkhatib Biradar Rohan Nagendrappa; Modern medicine faces the formidable challenge of cancer because of its ability to evade immune surveillance and cultivate resistance to conventional therapies. Cancer cells, when overexpressed with CD47, send a “don...; 关键词：CD47 Tyrosine Kinase Inhibitors Cancer Immune Evasion Tumor Microenvironment Targeted Cancer Therapy Immune Checkpoint Inhibitors

Bridging molecular advancements and clinical challenges in pediatric oncology: 《World Journal of Pediatrics》2025年第2期120-122,共3页Michaela Kuhlen Michael C.Frühwald; Open Access funding enabled and organized by Projekt DEAL.; Pediatric oncology has always been a dynamic and everevolving field dedicated to understanding and combating cancers in children and adolescents.While survival rates for many pediatric malignancies have improved signi...; 关键词：understanding combating cancers pediatric oncology pediatric malignancies molecular insights translating molecular insights effective treatm solid tumors rare cancers we

Radiation-induced rhinosinusitis:Mechanism research and clinical progress review: 《World Journal of Otorhinolaryngology-Head and Neck Surgery》2024年第4期324-332,共9页Chunge Zheng Longgang Yu Yan Jiang; National Natural Science Foundation of China,Grant/Award Number:81770978;Medicine and Health Science Technology Development Program of Shandong Province,Grant/Award Number:202207010780。; Objectives:Radiation-induced rhinosinusitis is a vital dose-limiting reaction in patients with head and neck malignancy.Unlike oral mucositis during or after radiotherapy,radiation-induced sinusitis is easily overlook...; 关键词：head and NECK CANCERS MUCOSITIS NASOPHARYNX cancer RADIATION-INDUCED RHINOSINUSITIS radiotherapy

Case series:Using laryngeal mask airway to enhance the radiological evaluation and staging of cancers involving the larynx:A novel technique: 《World Journal of Otorhinolaryngology-Head and Neck Surgery》2024年第4期345-349,共5页Abdullah Aljaafari Haytham Raad Aysegul Munar Ali H.Hasan Omar Sabra; The diagnosis and staging of head and neck tumors requires proper clinical,endoscopic,and radiological evaluation.Currently,imaging techniques such as Magnetic Resonance Imagining(MRI)and Computed Tomography(CT)are us...; 关键词：HEAD and NECK imaging HEAD and NECK tumors LARYNGEAL mask airway

Diagnosis of Digestive Tumors: Experience of Bangui (Central Africa Republic) about 112 Cases: 《Open Journal of Radiology》2024年第4期173-185,共13页Francky Kouandongui Bangue Songrou Timothée Mobima Elemence Eva Tapande Yakossa Epouse Maka Yannick Héritier Sombot-Soule Borel Tambala Stéphane Kouzou Judth Edwige Guiaba Kette Mokpondo Euloge Tapiade Bidan; Background: In the Central African Republic, several studies have addressed cancers with an imaging modality based exclusively on ultrasonography, due to the lack of modern imaging. The acquisition of a multi-bar scan...; 关键词：Digestive Cancers CT Scan Anatomopathology Bangui

Novel perspectives on the link between obesity and cancer risk:from mechanisms to clinical implications: 《Frontiers of Medicine》2024年第6期945-968,共24页Xiaoye Shi Aimin Jiang Zhengang Qiu Anqi Lin Zaoqu Liu Lingxuan Zhu Weiming Mou Quan Cheng Jian Zhang Kai Miao Peng Luo; supported by Macao Science and Technology Development Fund(FDCT)grants 0073/2021/A2,and 0009/2022/AKP to K.M.,Research Institute of Tsinghua,Pearl River Delta,ITPRD GBA Innovation Center.; Existing epidemiologic and clinical studies have demonstrated that obesity is associated with the risk of a variety of cancers.In recent years,an increasing number of experimental and clinical studies have unraveled t...; 关键词：OBESITY obesity-associated cancers cancer ris CARCINOGENESIS cancer prevention

Tricuspid mass-curious case of Li-Fraumeni syndrome:A letter to the editor: 《World Journal of Clinical Cases》2024年第33期6644-6646,共3页Mohammad S Al-Haggar Zahraa A Abdelmoneim; We focus specifically on the rare occurrence of cardiac thrombi in Li-Fraumeni syndrome(LFS).LFS is a hereditary risk to a diverse range of specific,uncommon,malignancies.Children and young adults have a heightened su...; 关键词：Li-Fraumeni syndrome CANCERS Cardiac thrombus Genetic counseling SURVEILLANCE

CANCERS