MUCOSITIS

作品数：30被引量：75H指数：5
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New insights into the mechanisms of modified Pulsatilla decoction in alleviating chemotherapy-induced intestinal mucositis
《World Journal of Gastroenterology》2025年第12期192-195,共4页Ajitha G Gopika Naresh Sachdeva 
Chemotherapy-induced intestinal mucositis(IM)is a prevalent complication affecting up to 80%of cancer patients undergoing treatment.Current therapies focus on symptomatic relief rather than addressing the underlying m...
关键词：Modified Pulsatilla decoction Intestinal mucositis Oxidative stress Gut microbiota TLR4/MyD88/nuclear factor kappa-B pathway Inflammatory response 
Modified Pulsatilla decoction alleviates 5-fluorouracil-induced intestinal mucositis by modulating the TLR4/MyD88/NF-κB pathway and gut microbiota
《World Journal of Gastroenterology》2025年第7期110-129,共20页Yi-Tong Qiu Xin-Yi Luo Ya-Feng Deng Xue Zheng Jian-Guo Qiu Lin-Sheng Zhang Xiao-Qi Huang Xue-Bao Zheng Hai-Yang Huang 
Supported by Basic and Applied Basic Research Foundation of Guangdong Province,No.2021B1515140043,No.2022A1515140124 and No.2023A1515140115.
BACKGROUND Modified Pulsatilla decoction(PD),a PD with licorice and ejiao,is a classic Traditional Chinese Medicine formula with significant efficacy in treating intestinal mucositis(IM)induced by tumor therapy.Howeve...
关键词：Modified Pulsatilla decoction Intestinal mucositis Oxidative stress Gut microbiota TLR4/MyD88/NF-κB pathway Inflammatory response 
Cost Assessment for Oncology Patients: Sodium Bicarbonate 2% Oral Solution Mouth Wash for Mucositis
《Open Journal of Preventive Medicine》2025年第1期1-12,共12页Nangrutai Chaiya Meredith Douglas Tyler Goins Samantha Chetosky Benjamin Kefas 
Background: Chemotherapy induced mucositis is one of the deterring factors influencing adherence to cancer treatment. Sodium bicarbonate mouth wash was recently shown to increase patients’ compliance. However, the co...
关键词：MUCOSITIS Sodium Bicarbonate 2% Mouth Wash CHEMOTHERAPY USP 795 
Radiation-induced rhinosinusitis:Mechanism research and clinical progress review
《World Journal of Otorhinolaryngology-Head and Neck Surgery》2024年第4期324-332,共9页Chunge Zheng Longgang Yu Yan Jiang 
National Natural Science Foundation of China,Grant/Award Number:81770978;Medicine and Health Science Technology Development Program of Shandong Province,Grant/Award Number:202207010780。
Objectives:Radiation-induced rhinosinusitis is a vital dose-limiting reaction in patients with head and neck malignancy.Unlike oral mucositis during or after radiotherapy,radiation-induced sinusitis is easily overlook...
关键词：head and NECK CANCERS MUCOSITIS NASOPHARYNX cancer RADIATION-INDUCED RHINOSINUSITIS radiotherapy 
Targeted inhibition of Gus-expressing Enterococcus faecalis to promote intestinal stem cell and epithelial renovation contributes to the relief of irinotecan chemotoxicity by dehydrodiisoeugenol
《Acta Pharmaceutica Sinica B》2024年第12期5286-5304,共19页Ruiyang Gao Bei Yue Cheng Lv Xiaolong Geng Zhilun Yu Hao Wang Beibei Zhang Fangbin Ai Ziyi Wang Donghui Liu Zhengtao Wang Kaixian Chen Wei Dou 
supported by the National Natural Science Foundation of China(No.82274329,82304991,82130115);the China Postdoctoral Science Foundation(No.2023M732336);the Shanghai Science and Technology Committee Sailing Program Foundation(No.23YF1442500,China).
Irinotecan(CPT11)chemotherapy-induced diarrhea affects a substantial cancer population due to b-glucuronidase(Gus)converting 10-O-glucuronyl-7-ethyl-10-hydroxycamptothecin(SN38G)to toxic 7-ethyl-10-hydroxycamptothecin...
关键词：IRINOTECAN Intestinal mucositis b-Glucuronidase Enterococcus faecalis Intestinal stem cells Epithelial regeneration Gus bacteriaehost eirinotecan axis Dehydrodiisoeugenol 
Eubacterium coprostanoligenes alleviates chemotherapy-induced intestinal mucositis by enhancing intestinal mucus barrier被引量：1
《Acta Pharmaceutica Sinica B》2024年第4期1677-1692,共16页Dongsheng Bai Jiawei Zhao Runde Wang Jiaying Du Chen Zhou Chunyang Gu Yuxiang Wang Lulu Zhang Yue Zhao Na Lu 
This work was supported by the National Natural Science Foundation of China(No.82373910,82204409);The“Double First-Class”University Project(CPU2022QZ20,China)。
Chemotherapy-induced mucositis represents a severe adverse outcome of cancer treatment,significantly curtailing the efficacy of these treatments and,in some cases,resulting in fatal conse-quences.Despite identifying i...
关键词：CHEMOTHERAPY MUCOSITIS Eubacterium coprostanoligenes MUC2 AUF1 
Author correction to"DNA damage repair promotion in colonic epithelial cells by andrographolide downregulated cGAS-STING pathway activation and contributed to the relief of CPT-11-induced intestinal mucositis"[Acta Pharmaceutica Sinica B 12(2022)262-273]
《Acta Pharmaceutica Sinica B》2023年第7期3177-3177,共1页
Association between the nutritional status and radiation pharyngeal mucositis in patients with head and neck cancer during radiotherapy:A longitudinal study被引量：1
《Journal of Nutritional Oncology》2023年第1期31-37,共7页Li-Chuan Zhang Yu-Jie Wang Bing Zhuang Tong Zhang San-Li Jin Meng Wan Dan Zhao Bao-Min Zheng hao-Wen Xiao Wei-Xin Liu Xiao-Long Xu Zhou Huang Yan Sun Ya-Ru Zhang Wei-Hu Wang Qian Lu 
This research was supported by the National Key Research and Development Project of China(No.2017YFC1309204);the Medical Nutrition Clinical Research Project of China International Medical Foundation(No.Z-2017-24-2110).
Objective Radiation mucositis,especially pharyngeal mucositis,severely affects the oral intake of patients of head and neck cancer(HNC)during radiotherapy.Whether the nutritional status affects the severity of pharyng...
关键词：Head and neck cancer RADIOTHERAPY MALNUTRITION GLIM criteria Radiation pharyngeal mucositis 
Babao Dan Alleviates 5-Fluorouracil-Induced Intestinal Damage via Wnt/β-Catenin Pathway被引量：3
《Chinese Journal of Integrative Medicine》2022年第11期1000-1006,共7页GUI Meng-xuan HUANG Bin PENG Jun CHEN Xi Ragunath Muthu GAO Ying WANG Rui-guo LIN Jiu-mao 
Supported by the Natural Science Foundation of Fujian Province,China(No.2019J01355);Xiamen Traditional Chinese Medicine Factory Co.,Ltd.(No.HX2016001)。
Objective:To evaluate the protective function of Babao Dan(BBD)on 5-flurouracil(5-FU)-induced intestinal mucositis(IM)and uncover the underlying mechanism.Methods:A total of 18 male mice were randomly divided into 3 g...
关键词：5-flurouracil Babao Dan body weight DIARRHEA intestinal mucositis Wnt/β-catenin pathway 
Wumei pills attenuates 5-fluorouracil-induced intestinal mucositis through Toll-like receptor 4/myeloid differentiation factor 88/nuclear factor-κB pathway and microbiota regulation被引量：4
《World Journal of Gastroenterology》2022年第32期4574-4599,共26页Dong-Xue Lu Feng Liu Hua Wu Hai-Xia Liu Bing-Yu Chen Jing Yan Yin Lu Zhi-Guang Sun 
Supported by the National Natural Science Foundation of China,No.81673795.
BACKGROUND Radiotherapy and chemotherapy can kill tumor cells and improve the survival rate of cancer patients.However,they can also damage normal cells and cause serious intestinal toxicity,leading to gastrointestina...
关键词：Wumei pills Gut flora Intestinal mucosal inflammation Mucosal barrier Short-chain fatty acids Intestinal permeability 
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